A heart attack from DNP. At what dose is this a risk? I've never heard of this from a low does of 250mg/day. Yet you recommend ECA, when pro athletes have also died from taking it over a recommended dose? Clearly both are dangerous if mproperly used, but why do people act like DNP is gonna cause you to melt or explode?
I'm sure what Pyes is reffering to is those that dont keep adequate carbs and water intake up which dnp removes both fast so don't be stupid and add the right carbs and plenty of water!
Pyruvate and the heart and glucose and insulin.
Cardiac metabolism and electromechanics of human heart.
Author Prasad K
Source Recent Adv Stud Cardiac Struct Metab, 10():119-37 1975
Abstract
The effects of substrates on the metabolic inhibitor-induced changes in the action potential and contraction of
papillary muscles obtained from patients undergoing corrective open-heart surgery were studied. Anoxia produced a
marked shortening of the action potential duration and a decrease in the resting potential, rate of rise of action
potential, effective refractory period, and contractility. In anoxic muscle, although glucose completely restored the
action potential duration, effective refractory period, and resting potential to control levels, it was unable to
completely restore the contractility to the control level. Substrate depletion and metabolic inhibitors (iodoacetate,
dinitrophenol) produced effects similar to that of anoxia, but at a faster rate. Glucose restored the action potential
and, to a lesser extent, contractility to the control level in dinitrophenol-treated muscle but was ineffective in so
doing the iodoacetate-treated muscle. Pyruvate, however, was effective in restoring the action potential and
contracility in iodoacetate-treated muscle. Pretreatment of the muscle with glucose and, particularly, with glucose
plus insulin prevented the combined effects of anoxia and lack of glucose on the action potential and contractility
for a prolonged period. These results suggest that intravenous infusion of glucose and insulin before and during
surgery might prevent or reduced the effect of anoxia on the electrical and mechanical activity of the heart during
open-heart surgery.
Pyruvate was able to restore the action potential (charge) of cells treated with DNP!
Your not an open heart surgery patient i'd imagine your symptoms will not be as severe as theres! and verry little with 3 Tablespoons glycerol 3x a day.
1g Pyruvate 3x a day.
Taurine at 3g a day.
DNP at 36 hour intervals.
For what it's worth, I don't completely agree with this, Extensive studies by P.N. Taussig have shown that dinitrophenol does not reduce cardiac
glycogen at all and that, on this point, it differs completely from thyroxine.
(of course you have to keep carbs in your diet and the right ones so don't be stupid and lower carbs to nothing)