Yes some have reported magic happening at 15 mg a week that's like 150 clams a week. May just hit the reta first.I like retatrutide myself. Microdosed for all the health benefits. I don't care about appetite suppression. When I tried sema, even microdosing during contest prep was too much suppression. Retatrutide still allows me to eat, just takes the craving edge off. The only issue I see with tirzepitide, is you are using it for the appetite suppression, doses can get kind of high.
Increase in RHR and or irregular beats.What heart issues with RETA? Certainly not at lower doses. You can ask 100 people and you will get 100 different answers on RETA vs SEMA vs TIRZ because everyone responds differently. The only way to know for sure is to try each one alone over time, slowly ramping and see which one works best for you (benefits vs sides). One low dose of TIRZ can send someone to the ER with gastroparesis, and in another it take 3x that dose just to have an effect.
I haven't used any of these, but my wife is currently using tirz @ 5 mgs per week (she started at a much lower dose)... she has lost 35 pounds in 3 months with basically zero side effects.
In the NEJM study the incr in HR was about 3 - 4 BPM in the 4 mg/wk dosing, the overall cardiac sides were near zero in dosing under 8 mg/wk. None of my clients or friends using RETA in the 3 mg/wk range are experiencing any side (GI or cardiac) just fat loss and an the edge off of food cravings. Again, until you try it, you won't know, but if dosing starts at 0.5 mg 2x/wk and slowly ramps until you reach the desired effect, the risks are low. One of my clients on TIRZ has lost so much weight and looks sick, and is feeling that way as was an older client on TIRZ. Since insurance covers the TIRZ for them, they don't want to try RETA. IMO, clinicians over prescribe these drugs and ramp too quickly, and don't individualize treatment. If you are prone to SVTs or NSVTs, or frequent ectopies (HCM or other cardiac issues), then proceed cautiously. Still less cardiac risk than CLEN, EPH or DNP.Increase in RHR and or irregular beats.
Certainly with genetics drugs aging metabolism etc everyone is going to react differently.
I am going after the reta most likely at .5mg a week.
I am off work another week but diet isn't super optimal as I am eating out a couple times a week.
I do agree small doses over long periods of time to see results.
I have no goal of dumping 30 lbs in a few weeks and getting that old looking wrinkled face.
I see a lot of women losing tons of weight at work. I know they are taking weg or Oz as they have lost so much weight their faces sag and they look like they have a flat book looking ass.
We work in an open office area and I see them hit the head like 10 times a day.