Triz or ret?

[Massive G]

Second week of 9mg reta... appetite is gone again. I eat...but by 3rd meal I don't want too. I try for 5 meals, 2500 cal

I lost about 20 lbs in 3 weeks on the retatrutide. 5mg eod. I do think I am an outlier I think as I am on 336 T4 replacement dose and found an article reference to semaglutide increased thyroid med activity by 1/3.
I am starving all the time. I may try to up the dose but did drop my thyroid meds to 224 mcg and gained all the weight back. I am curious on others doses especially with tirzepatide as many are going up to 12 mgs a week to get results.

 

[DogMogul]

Second week of 9mg reta... appetite is gone again. I eat...but by 3rd meal I don't want too. I try for 5 meals, 2500 cal

I mean - lol

Sounds like the peptide is doing exactly what it’s supposed to.

Did you need to increase dosage to maintain appetite suppression?


Sent from my iPhone using Tapatalk

 

[big bx]

I mean - lol

Sounds like the peptide is doing exactly what it’s supposed to.

Did you need to increase dosage to maintain appetite suppression?


Sent from my iPhone using Tapatalk

Yea. Started at 3 or 4mg in in October. Id have to look back.

 

[big bx]

I lost about 20 lbs in 3 weeks on the retatrutide. 5mg eod. I do think I am an outlier I think as I am on 336 T4 replacement dose and found an article reference to semaglutide increased thyroid med activity by 1/3.
I am starving all the time. I may try to up the dose but did drop my thyroid meds to 224 mcg and gained all the weight back. I am curious on others doses especially with tirzepatide as many are going up to 12 mgs a week to get results.

Didn't know that about thyroid. But, makes sense for the RHR increase I get.

 

[jhotsauce7]

I suggest twice a week split total dose, seems to limit potential GI sides, if there are any. Usually between 1 - 3 mg/wk is plenty for what everyone here is trying to achieve and limit sides. I've found it lasts about 30 days in the fridge without loss of potency. Be careful how you mix it so it doesn't foam and you should be able to find it for about $11/mg.

Curious what you meant by so it doesn’t foam.. never heard that before but I have heard not to vigorously shake when reconstituting.. like swirl it slowly..

planning on adding 1mg Reta (split 2x EW) on top of the 1mg sema I’ve been using (12 weeks at that dose) in a couple weeks to see if that steps my metabolism up a notch.

 

[genetic freak]

Curious what you meant by so it doesn’t foam.. never heard that before but I have heard not to vigorously shake when reconstituting.. like swirl it slowly..

planning on adding 1mg Reta (split 2x EW) on top of the 1mg sema I’ve been using (12 weeks at that dose) in a couple weeks to see if that steps my metabolism up a notch.

Foaming typically occurs when you don't remove the vacuum seal and inject the bacteriostatic water in too quickly. Foaming is a reaction of the peptide. Meaning, it is breaking down.

Another thing to think about when it comes to peptides is not all can be mixed in the same syringe. If your solution turns cloudy, that is a chemical reaction between the two peptides, which is not good. A couple that do not mix well with virtually everything are insulin and melanotan. I have seen melanotan crystalize the solution when mixed with some. Couldn't push it through the needle with all my might. I actually cracked the flange on the syringe trying.

 

[danrojigga]

Reta just do it. Start low and keep increasing every 4 weeks. That is if you’ve got a lot to lose. Probably could just cruise low dose if it’s just a little to lose. The shit is magical and doesn’t have near the stomach issues as the others.

 

[The other Snake]

I have no goal of dumping 30 lbs in a few weeks and getting that old looking wrinkled face.

I see a lot of women losing tons of weight at work. I know they are taking weg or Oz as they have lost so much weight their faces sag and they look like they have a flat book looking ass.

Ok, old post but I have started to see this in a few women that are on GLP-1s. Not sure why but some women are losing weight but not the thigh dimples. I'm guessing the fat between the skin and those little connective tethers are not reducing.

I'm noticing the old look in the jowls and neck on the 40+ women. Probably doesn't help they are finding up to 1/3 of the weigh loss is muscle. That can't be good for overall body composition.

 

[genetic freak]

That is because they still eat shit, they just eat less of it. Instead of eating 3000-4000 calories of processed bullshit, they are eating 800-1000 calories of processed bullshit. No lifestyle changes. They are going to run into the same problems you get with the elimination diets. Everything is great at first. Fat loss, improved health markers then it catches up to them. They completely wreck their endocrine and metabolic systems. They have less muscle, lower bone density and are still insulin resistant.

 

[Tuffoldman]

Not trying to hijack this thread but I didn't want to start a new one asking basically the same information.


I've used semiglutide and of course helps a lot with my food cravings and food noise but it gives me ridiculous amount of acid reflux / indigestion. I came off of ppi's a few months ago and I would never ever go back on those again. I have trouble enough as it is with heartburn and reflux and I'm trying to manage the best I can through diet, some other digestive aids such as aloe vera juice and coconut water.

I keep reading all this different information on Reta and the dosage and pricing seems way out of the ballpark but just wondering; is anybody using very low dose such as quarter of a milligram a couple of times a week and how is that working for you?

Also I'm on high blood pressure medicine I take 50 mg of Losartan in the morning and 25 mg before I go to bed. Controls my blood pressure pretty well. I have always had blood pressure issues going back to I was 17 trying to join the Air Force my blood pressure back then was in the 130s. My diastolic is still around 80 but my systole can go up as high as 150 Plus. No real heart conditions other than just high blood pressure. I heard that Reta can push blood pressure up but just wondering at lower doses what is the possibility of causing heart damage?

Also if I low dose Reta compared to 1 mg of semiglutide am I going to run into the same heartburn issues? I haven't used this and probably a month and a half the one I did it was tragic.


I am an eater, going back to the days many years ago when I was 300 lbs and I'm still a fat kid inside so I'm always hungry. I would like something to curb my appetite a little bit but from what I'm reading Reta has an effect on stored body fat. I hover somewhere between 10 and 12% but would like to get down to 7 or 8%. I do a little bit of cardio hate it hate it hate it. I eat pretty clean but sometimes in the evening I get bored and eat more than I should. I don't care about weight loss necessarily just would like to see some good fat loss. I have different goals in mind now that I'm almost 60 I'm looking to get more shredded than bigger. I have just never been genetically gifted in that department so I thought if I get shredded kind of changes my goals and look.


Right now all I take is testosterone 200 mg a week which I've been cruising on for decades.

Any thoughts? Would I be benefiting from adding very low dose Reta and maybe cruising at 200 mg or so a week of masteron? I would like to be a little more muscular looking but not necessarily bigger if that makes sense.

At this point in my life I'm trying to stay healthy but still enjoy the benefits of looking many years younger than how old I am. It's important to the business I'm in very very important.

Any and all advice is favorable. I was thinking about throwing GH back in but wondering if using sermorelin peptide instead would be more favorable. Avoid some of the side effects and water retention from GH but still get the benefit of natural gH production.

Money is important factor but willing to spend what I need to if I'm going to see benefits from making some pharmaceutical changes.


Thank you in advance

 

[jhotsauce7]

Not trying to hijack this thread but I didn't want to start a new one asking basically the same information.


I've used semiglutide and of course helps a lot with my food cravings and food noise but it gives me ridiculous amount of acid reflux / indigestion. I came off of ppi's a few months ago and I would never ever go back on those again. I have trouble enough as it is with heartburn and reflux and I'm trying to manage the best I can through diet, some other digestive aids such as aloe vera juice and coconut water.

I keep reading all this different information on Reta and the dosage and pricing seems way out of the ballpark but just wondering; is anybody using very low dose such as quarter of a milligram a couple of times a week and how is that working for you?

Also I'm on high blood pressure medicine I take 50 mg of Losartan in the morning and 25 mg before I go to bed. Controls my blood pressure pretty well. I have always had blood pressure issues going back to I was 17 trying to join the Air Force my blood pressure back then was in the 130s. My diastolic is still around 80 but my systole can go up as high as 150 Plus. No real heart conditions other than just high blood pressure. I heard that Reta can push blood pressure up but just wondering at lower doses what is the possibility of causing heart damage?

Also if I low dose Reta compared to 1 mg of semiglutide am I going to run into the same heartburn issues? I haven't used this and probably a month and a half the one I did it was tragic.


I am an eater, going back to the days many years ago when I was 300 lbs and I'm still a fat kid inside so I'm always hungry. I would like something to curb my appetite a little bit but from what I'm reading Reta has an effect on stored body fat. I hover somewhere between 10 and 12% but would like to get down to 7 or 8%. I do a little bit of cardio hate it hate it hate it. I eat pretty clean but sometimes in the evening I get bored and eat more than I should. I don't care about weight loss necessarily just would like to see some good fat loss. I have different goals in mind now that I'm almost 60 I'm looking to get more shredded than bigger. I have just never been genetically gifted in that department so I thought if I get shredded kind of changes my goals and look.


Right now all I take is testosterone 200 mg a week which I've been cruising on for decades.

Any thoughts? Would I be benefiting from adding very low dose Reta and maybe cruising at 200 mg or so a week of masteron? I would like to be a little more muscular looking but not necessarily bigger if that makes sense.

At this point in my life I'm trying to stay healthy but still enjoy the benefits of looking many years younger than how old I am. It's important to the business I'm in very very important.

Any and all advice is favorable. I was thinking about throwing GH back in but wondering if using sermorelin peptide instead would be more favorable. Avoid some of the side effects and water retention from GH but still get the benefit of natural gH production.

Money is important factor but willing to spend what I need to if I'm going to see benefits from making some pharmaceutical changes.


Thank you in advance

I had some reflux issues on 1mg sema for a bit, but then it just seemed to resolve itself.. not sure what changed.
I had been off omeprozol for a year but had to start taking it for a couple months early on when using sema.
I’m still at 1mg sema, and maybe like 4 months In at this dose. I still have an appetite and can get my protein in but no urge to over eat.. no urge to drink a beer or two on the weekend either.
I’m gonna Guinea pig adding in 1mg Reta, and build to 2mg Reta for 16 weeks total to see if I can drop a couple percentages of bf. I should probably make a separate post or log it but I’m terrible at being consistent with log check ins. I’ll try to document how it goes none the less

After a shoulder tear last winter I put on a bit of body fat that I’m working to shed.. I was probably 12% before the injury then between that and having a kid, training and diet got blown up for 6-8 months at least. I dropped 30lb after surgery (April - June just on TRT + 125mg deca, 10mg var, bpc157 and slu-pp), then added sema around June 1. Hoping to lose another 10-12 lb of adipose and then recomp and add 8-10lb lbm.. I think Reta is going to be a game changer based on what Gf Has posted here and on other boards.

@ GF - how critical is the daily microdosing vs 2x a week. I feel like since I’m running in conjunction with sema that as long as I’m still getting the health benefits I’m not worried about anything with appetite, as that’s pretty squared away.

 

[genetic freak]

@jhotsauce7 I will address yours first, since this will be pretty quick. I think 2x a week vs microdosing when it comes down to total mg being the same will be pretty damn close when it comes to health benefits. I really do. You would likely see a benefit in microdosing just from more stable blood levels, but I don't think it would be significant enough to really tell. However, I think a bolus dose 2x a week would have much more significant impact on appetite suppression over microdosing. At least that is what I have observed.

@Tuffoldman I really haven't seen anyone have much of an increase in blood pressure using reta, but that doesn't mean it isn't possible. It is common for those to experience a slight heart rate elevation and in your case with the history of high blood pressure this could lead to an increase. How much, no idea and would likely be dose dependent.

I think .25 mg 2-3x a week is an effective dose. I actually know some pretty smart coaches who are dosing it at .125 mg a day and seeing health benefits, so you would be right there. Of course, you would see more fat loss at higher doses and maybe this is something you could experiment with. Try the lower dose for 3-4 weeks and see how things go then bump it up slightly. Maybe start at .25 mg 2x a week then go to 3x a week.

As for the acid reflux, if you are not taking apple cider vinegar, you should start. You don't have to drink that nasty shit. The caps and tabs WORK JUST AS WELL. I will stand on that hill. I have had more success weaning people off PPIs using ACV than anything else. Two caps or tabs in the morning and if you are really bad, throw in another two in the afternoon.

As lean as you are, GH sides should be nearly non-existent, as long as you are using less than 6 iu. Control your carb intake. Use a GDA if needed (I love berberine, but it can cause some acid reflux), but the reta will definitely help in this department. I was able to run all the way to 18 iu with no edema and just a slight bit of tingling in the left fingers on reta and SLU.

While masteron is a relatively safe compound, sometimes a DHT can cause some GI distress. If you add it in and a couple weeks later you start having acid reflux issues again, pull it or add in glutathione a couple times a week.