sassy69
TID Lady Member
- Aug 16, 2011
- 1,067
- 398
I'm starting this journal to record my experiences w/ TB-500 or Thymosin beta 4. Below is a block of description about it, but the impetus for this was some input by TID member, Times Roman in this thread about dealing w/ tendonitis.
http://www.theironden.com/threads/51-Bicep-Tendonitis?p=161252&viewfull=1#post161252
My interest started with the tendonitis angle, but in the time since I ordered some TB-500 per TR's suggested protocol, I started wondering of it would help w/ some other recent issues I've had. I moved to Chicago a couple months ago and in the process have done a LOT of walking and had developed a pain in the middle of both my feet, in addition to some ongoing plantar fasciitis. I decided to google "TB-500 foot pain" and found on Professional Muscle where someone related his wife's experience w/ it. She, being a distance runner had tried it to deal w/ plantar fasciitis. This piqued my interest because my feet are a mess.
For context, I'm 47, have been lifting since 1981 and competing in women's bodybuilding between 2000 - 2010. I developed my first tendonitis around 1991 in my elbows and at this point, any continued arm work will start it flaring up to the point that I might actually drop the weight if it hurts too much. I've got hereditary bunions and have already had 3 surgeries to deal w/ it. Currently isn't a primary issue. But I've also been dealing w/ plantar fasciitis in both feet since around 2007 and was diagnosed 2 weeks ago w/ 2 neuromas (inflamed nerve in the middle of my foot) on the right foot and one on the left. The doc game me 3 shots of cortisone to see if it would reduce the inflammation, but its not really doing that much. According to the doc, the next thing to deal with it is surgery - basically get it cut out. Not really what I'm looking for at the moment. I also have a jacked right rotator cuff - I had arthroscopic surgery in 2008 when they originally thought I had a pinhole tear in the rotator. They never found any tears but cleaned up a bunch of frayed tendon, cleaned out some arthritis and shaved down my clavicle to reduce impingements resulting from transient inflammation. It healed great, but I managed to jack it again doing heavy Arnold presses a week before my last competition in 2010 - meaning executing an unsupported lift while being completely depleted going into peak week. 2 yrs later its still an issue. And a variety of tendonitis from general wear & tear. I've cut way back on my lifting partly due to my work schedule and relocation to a new city and also in trying to drop some muscle mass to compete in a smaller competition category. So even w/ the time off, I still have regular flare ups of all of this stuff.
The list of specific issues:
- wrist tendonitis - left & right
- elbow tendonitis - left & right
- right shoulder irritation - tends to propagate to a spastic upper back and neck
- tweaky knees - left & right
- ankles & shins tend to get tight from the plantar fasciitis
- left heel always hurts (plantar fasciitis)
- left middle of the foot - neuroma that generally makes my middle toes get nerve shocks / numbness
- right middle of the foot - supposedly 2 neuromas that always hurt - I walk to / from work so that doesn't help
Also in pursuit of dropping some lean muscle mass and prepping for a possible 5K run (keeping in mind I stopped doing any sort of interval cardio back in 2005...), I've started working on building up to running a couple miles through increased duration interval cardio on a treadmill. Yea, my feet hurt.
The protocol I will be following is pretty simple and as TR recommended:
Week 1 (day 1): 5mg (reconstituted w/ 1ml bacteriostatic water) injected subQ in the ab area
Week 2 - 5 (every 7th day): 2.5 mg (5 mg bottle reconstituted w/ 1ml bac water = 0.5 ml bac water per injection) injected subQ in the ab area
Week 6 - whenever I run out: 2.5 mg every other week (every 14th day) injected subQ in the ab area.
What is TB-500? (stolen from online)
TB-500 (Thymosin beta-4) is not a growth factor; rather, it is a major actin regulating peptide. TB-500 has been found to play an important role in protection, regeneration and remodeling of injured or damaged tissues. The gene for TB500 has also been found to be one of the first proteins to be up-regulated after a wound occurs.
Thymosin Beta 4 is a synthetic version of the naturally occurring peptide present in virtually all cells, Thymosin Beta 4 TB-500. It is a first-in-class peptide candidate that promotes the following:
* Endothelial (blood vessels) cell differentiation
* Angiogenesis (growth of new blood cells from pre-existing vessels) in dermal tissues
* Keratinocyte migration
* Collagen deposition; and
* Decreases inflammation.
Thymosin Beta-4, synonymously referred to as TB-500, offers many benefits to the equine world in performance enhancement. Recent trials by some of the world’s leading trainers have been credited by a huge boost in their race-day results, something long desired in racing worldwide.
These trials along with clinical trials have indicated the following benefits associated with the use of Thymosin Beta 4:
* Relaxed muscle spasm
* Improved muscle tone
* Increase the exchange of substance between cells
* Encourage tissue repair
* Stretches connective tissue
* Helps maintain flexibility
* Reduces inflammation of tissue in joint
* Enhances nutritional components in the animal
* Prevents the formations of adhesions and fibrous bands in muscles, tendons and ligaments.
http://www.theironden.com/threads/51-Bicep-Tendonitis?p=161252&viewfull=1#post161252
My interest started with the tendonitis angle, but in the time since I ordered some TB-500 per TR's suggested protocol, I started wondering of it would help w/ some other recent issues I've had. I moved to Chicago a couple months ago and in the process have done a LOT of walking and had developed a pain in the middle of both my feet, in addition to some ongoing plantar fasciitis. I decided to google "TB-500 foot pain" and found on Professional Muscle where someone related his wife's experience w/ it. She, being a distance runner had tried it to deal w/ plantar fasciitis. This piqued my interest because my feet are a mess.
For context, I'm 47, have been lifting since 1981 and competing in women's bodybuilding between 2000 - 2010. I developed my first tendonitis around 1991 in my elbows and at this point, any continued arm work will start it flaring up to the point that I might actually drop the weight if it hurts too much. I've got hereditary bunions and have already had 3 surgeries to deal w/ it. Currently isn't a primary issue. But I've also been dealing w/ plantar fasciitis in both feet since around 2007 and was diagnosed 2 weeks ago w/ 2 neuromas (inflamed nerve in the middle of my foot) on the right foot and one on the left. The doc game me 3 shots of cortisone to see if it would reduce the inflammation, but its not really doing that much. According to the doc, the next thing to deal with it is surgery - basically get it cut out. Not really what I'm looking for at the moment. I also have a jacked right rotator cuff - I had arthroscopic surgery in 2008 when they originally thought I had a pinhole tear in the rotator. They never found any tears but cleaned up a bunch of frayed tendon, cleaned out some arthritis and shaved down my clavicle to reduce impingements resulting from transient inflammation. It healed great, but I managed to jack it again doing heavy Arnold presses a week before my last competition in 2010 - meaning executing an unsupported lift while being completely depleted going into peak week. 2 yrs later its still an issue. And a variety of tendonitis from general wear & tear. I've cut way back on my lifting partly due to my work schedule and relocation to a new city and also in trying to drop some muscle mass to compete in a smaller competition category. So even w/ the time off, I still have regular flare ups of all of this stuff.
The list of specific issues:
- wrist tendonitis - left & right
- elbow tendonitis - left & right
- right shoulder irritation - tends to propagate to a spastic upper back and neck
- tweaky knees - left & right
- ankles & shins tend to get tight from the plantar fasciitis
- left heel always hurts (plantar fasciitis)
- left middle of the foot - neuroma that generally makes my middle toes get nerve shocks / numbness
- right middle of the foot - supposedly 2 neuromas that always hurt - I walk to / from work so that doesn't help
Also in pursuit of dropping some lean muscle mass and prepping for a possible 5K run (keeping in mind I stopped doing any sort of interval cardio back in 2005...), I've started working on building up to running a couple miles through increased duration interval cardio on a treadmill. Yea, my feet hurt.
The protocol I will be following is pretty simple and as TR recommended:
Week 1 (day 1): 5mg (reconstituted w/ 1ml bacteriostatic water) injected subQ in the ab area
Week 2 - 5 (every 7th day): 2.5 mg (5 mg bottle reconstituted w/ 1ml bac water = 0.5 ml bac water per injection) injected subQ in the ab area
Week 6 - whenever I run out: 2.5 mg every other week (every 14th day) injected subQ in the ab area.
What is TB-500? (stolen from online)
TB-500 (Thymosin beta-4) is not a growth factor; rather, it is a major actin regulating peptide. TB-500 has been found to play an important role in protection, regeneration and remodeling of injured or damaged tissues. The gene for TB500 has also been found to be one of the first proteins to be up-regulated after a wound occurs.
Thymosin Beta 4 is a synthetic version of the naturally occurring peptide present in virtually all cells, Thymosin Beta 4 TB-500. It is a first-in-class peptide candidate that promotes the following:
* Endothelial (blood vessels) cell differentiation
* Angiogenesis (growth of new blood cells from pre-existing vessels) in dermal tissues
* Keratinocyte migration
* Collagen deposition; and
* Decreases inflammation.
Thymosin Beta-4, synonymously referred to as TB-500, offers many benefits to the equine world in performance enhancement. Recent trials by some of the world’s leading trainers have been credited by a huge boost in their race-day results, something long desired in racing worldwide.
These trials along with clinical trials have indicated the following benefits associated with the use of Thymosin Beta 4:
* Relaxed muscle spasm
* Improved muscle tone
* Increase the exchange of substance between cells
* Encourage tissue repair
* Stretches connective tissue
* Helps maintain flexibility
* Reduces inflammation of tissue in joint
* Enhances nutritional components in the animal
* Prevents the formations of adhesions and fibrous bands in muscles, tendons and ligaments.
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