Nolva did exactly jack shit for my bloat from dbol. It helped with preventing gyno, but I still had all that estrogen circulating in my body. Nolva mainly binds to breast tissue and doesnt do much for anywhere else. That is why it is used for treatment of breast cancer. If it works for you guys then that is cool, but I dont really see how. Adex or aromasin are the only things that help me with bloat, and letro to treat existing gyno.
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Some very important yet simplistic distinctions should be made between AIs and SERMs.
1) It's well established the SERMS, Relofen, Tamoxifen and Clomiphere exhibit differing effects (agonists, antagonists) based upon not only their chemical structure but also the TISSUE itself. Thus while one SERM may have agonist uterine effects and antagonistic peripheral effects, the results from another SERM may be the antithesis.
Similarly considerable variation exists between individuals especially at lower dosages. For this reason some people may develop a worsening of bloat" with Tamoxifen especially when higher doses are used.
With that being said what is really important to realize, SERMs are most effective for the treatment of LOCAL E-2 "complications" such as; gynecomastia and PCT, because the amount of
tissue binding required to effect change is relatively small.
However AIs are better suited for SYSTEMIC E-2 complication like; bloat, because the amount of tissue involved is quite large! (Bloat is primarily the consequence of an elevated E-2 which causes a relative ADH increase in addition to enhanced capillary permeability)
Ergo while some notice an improvement of Bloat with SERM therapy others may NOT. Alternatively the overwhelming majority of mates using AIs for bloat will notice considerable benefit.
So if "BLOAT" is the AAS complication your wanting to treat an AI would be considered first line therapy, IMO. I prefer Anastrozole for a variety of reasons, including lipid changes, half life, efficacy, cost (about a 50c / pill at Costco)
Regs
jim