Here is some high level notes from D himself....
Basic guide:
1 cap/day: barely any effect. You won't feel it or see much result. This is simply a low loading dose to see if you have any allergies to it. Females or smaller-sized men may find that 1 cap/day does work, but most won't.
2 caps/day: you're getting started. You'll feel slight warmth, especially at night or when resting after eating carbs. You'll get a good effect from long-term use, but it's not a high dose.
3 caps/day: this is a high dose and should result in heat sensations after a few days at this level, especially at night, after exercise, or after eating. After a few days on 3/day, you'll feel hot. You'll sweat at night and find a strong effect. Don't go higher unless you're a veteran who's thoroughly experienced. NEVER START AT THIS DOSE! Build up to it gradually. I do not suggest going higher; 2/day is conservative and 3/day is high. A *few* men use 4, but that's for veterans and big guys.
Never, ever use alcohol, drugs, or powerful diuretics on DNP. Use of caffeine is fine if you keep hydrated. You WILL retain water on DNP; don't judge DNP by the scale weight every day. Some guys have even GAINED a pound or two at first--it's water weight. This phenomenon is normal, and it'll go away when you stop taking
DNP, as long as you keep carbs low for the first week after you stop.
Use supplements wisely. Adding extra antioxidants like alpha lipoic acid is always a good idea, and DNP works very well with products like fish oil and energy stimulants.
DNP is strong, but you still have to exercise moderately and do intelligent dieting. I never suggest a totally carb-free approach to DNP (you'll feel hypoglycemic), but a reduction in carbs seems to work well.
Lower carbs will also reduce unpleasant heat effects, especially if you avoid carbs in the evenings.Using DNP for more than a couple of weeks generally causes temporary slowdown in metabolism. At two weeks in, either take a 1-2 week break, or manage your thyroid with a thyroid-boosting supplement like T3
Lots of guys write me and ask why their DNP works "less" after 2-3 weeks than it did at first. Of course, nearly all of them assume it's an issue with the DNP (and want me to fix it!), when it turns out they've neglected to account for metabolic down-regulation.