Low dose primo

[Wilson6]

He is right. I took primo off and on over a year. More on then off. When I had my hormones checked My estrogen wasn’t even registering. It tanked my testosterone and progesterone also. I see you’re going to run T w/ it. I didn’t till the last few months.
I think I’m in that perimenopause phase. My brain fog has been horrible! Struggling to find my words sometimes. I’m still trying to get straight 4 months later with HRT.

Have to run T with it, older women probably a low dose E2 patch and progesterone.

 

[Wilson6]

Can I ask why you’re not concerned about E2? It does have its place/need, and arguably as we are older as it is somewhat neuroprotective … talk to any post menopausal woman and if their honest they’ll tell you their brain went down hill
Afterwards…

Neurotrophic and Neuroprotective Actions of Estrogen: Basic Mechanisms and Clinical Implications - PMC

Estrogen is an important hormone signal that regulates multiple tissues and functions in the body. This review focuses on the neurotrophic and neuroprotective actions of estrogen in the brain, with particular emphasis on estrogen actions in the ...

pmc.ncbi.nlm.nih.gov

Anyhow,
To your original question, MOST would say run primo at 1:1 with test, BUT, you will need to check your E2 levels as this is where it really varies with peoples response… then one finds out if they can run it higher or need to lower it… as @Littleguy just posted some can run it higher than their test, if I did that my e2 would crash and instead its always 75% of my test

Some of the women in their 20's at the gym, based on how they act, train and talk must already be menopausal, social media induced.

 

[Glycomann]

It differs for everybody. I run it like this: 300 test, 225 primo, 100 nandrolone blend. I've also run it as a TRT+ at: 200 Test C, 100 Primo. It might change though since I seem to be making less estrogen recently.