Synergy is something to take into account. Some people are talking about high doses and how the sides got out of control. What else were you running with the tren?? and at what dose's??? High test+high tren=bad sides for me. I'm talking 1g a week of test e with 800mg of tren e and I was about to go bat shit crazy, but I stuck it out. On the flip side low test+high tren was amazing, 300mg a week of test e with 100mg ed, 700mg/wk of tren a and it was all good. Only negative side was night sweats, I ran that for 12 weeks. I felt like I could tear down they gym everyday on that cycle. Who knows what the pros do, all anyone can ever do is speculate about the dose's and stacks they run. If they told everyone the truth then we'd all be 300lbers on stage. To go over 100mg ed of tren a seems excessive, but to each is there own. When negatives start to outweigh the benifits, it would be time to moderate imo. Talk about people dropping dead from abuse.. Can't say that I'd argue that, but what are the full circumstances of said abuse??? Oh some dude ran one cycle of a crazy amount of tren then fell over dead... Mmmmm I dont think so. Seems like it takes a prolonged amount of time for abuse to show its face and catch up to someone. If someone is a pro and they die, well they've had to be on gear for years to get to pro level. Not to say that one cycle couldnt cause permament damange to ones body, but most of us here are probably shut down for life and will live by the pin full of test till our end of days.