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Weight loss drugs, why do I hate them?

SAD

SAD

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Feb 3, 2011
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I have a visceral reaction to hearing people brag about how much weight they’ve lost and how easy it is with GLP drugs.

My first thought is that if all they do is take away cravings and limit your intake, then all it takes is discipline and you’re literally bragging about being lazy and cheating.

Then I think, well shit dude, I’m on gear. That’s cheating right? Isn’t that hypocrisy at its finest? Pot -> kettle, kettle -> pot?

And then I come back around and realize that all the gear in the world doesn’t give you the dedication to show up every day, eat every meal, abstain from every vice, etc.

I don’t say anything to anyone about it. I keep it all bottled up and just pretty much hate the new skinny-fat fucks who still haven’t changed a damn thing in their life besides an injection.

I’ve always been a huge advocate for fatties taking the initiative to do ANYTHING to help themselves, like walking, cleaning up their diet incrementally, joining a gym, etc. I’ve gone out of my way to encourage people who are actually doing something real, because I mean it and I also think it’s motivating to have a big meathead quietly say “hey, you’re doing awesome, I’ve seen the progress. Keep it up brother/sister.” But this feels different to me.

This is also not meant to strafe the bodybuilding and fitness crowd using it, although I’d like to know why, Barney style. Break it down for me why Reta is better than me just eating with discipline.


Tell me why it’s different, better, the same, worse. Tell me I’m being a Karen. Hopefully someone understands where I’m coming from.
 
M

Massive G

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Apr 10, 2020
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I have a visceral reaction to hearing people brag about how much weight they’ve lost and how easy it is with GLP drugs.

My first thought is that if all they do is take away cravings and limit your intake, then all it takes is discipline and you’re literally bragging about being lazy and cheating.

Then I think, well shit dude, I’m on gear. That’s cheating right? Isn’t that hypocrisy at its finest? Pot -> kettle, kettle -> pot?

And then I come back around and realize that all the gear in the world doesn’t give you the dedication to show up every day, eat every meal, abstain from every vice, etc.

I don’t say anything to anyone about it. I keep it all bottled up and just pretty much hate the new skinny-fat fucks who still haven’t changed a damn thing in their life besides an injection.

I’ve always been a huge advocate for fatties taking the initiative to do ANYTHING to help themselves, like walking, cleaning up their diet incrementally, joining a gym, etc. I’ve gone out of my way to encourage people who are actually doing something real, because I mean it and I also think it’s motivating to have a big meathead quietly say “hey, you’re doing awesome, I’ve seen the progress. Keep it up brother/sister.” But this feels different to me.

This is also not meant to strafe the bodybuilding and fitness crowd using it, although I’d like to know why, Barney style. Break it down for me why Reta is better than me just eating with discipline.


Tell me why it’s different, better, the same, worse. Tell me I’m being a Karen. Hopefully someone understands where I’m coming from.
Hey I completely understand. When these first came out I was like who the fuck wants to make themselves nauseous and sick so they can't eat?
Sema now the model t of them all was the worst. Then came tirzepatide which kind of never got a fair shake since retatrutide came out.

Now I see your point as a lot of guys are using this stuff to lose tons of weight. But some of these guys on the boards were fatties and taking large doses and losing tons of fat and muscle.

There is a hidden health movement hiding in this that a lot of us who are wrecking our insulin sensitivity with GH slin and AAS. But we are microdosers taking small amounts less than 2 mg a week and enhanced glucose metabolism as well as cholesterol reduction and improvement in kidney function.

I recently started back on retatrutide.
Been playing with several different GH
stimulation compounds due to the reduced supply of GH and it has went well. Mk677 which usually turns me into a sloppy sleepy mess was completely tolerable with microdoses of tirzepatide.

Same when I rotated to tesamorelin and cjac 195 ipamorelin.
The only thing I don't like about tirzepatide is I got acid reflux and it made it a struggle to eat and get all me water in.

Fast forward to 2 weeks ago started on black tops 6 ius EOD and bam call me rip van winkle fucking sleepy as fuck.

Added back in .125 mcg retatrutide every 3rd day full of energy bouncing around clear head and no brain fog or fatigue.

I got a bit fluffy over the holidays had 3 weeks off work so trained my ass off loaded on food weights and AAS and the GH stims and shot up to 310. That's why I started the tesamorelin initially to burn some visceral fat and my gut got a bit distended especially with the fact I was taking 20 ius lantus to load up.

I think most people take way too much of these compounds and everyone reacts to the compounds differently.

I will never go over 2 mg a week if I ever get there. This time last year, I started on low dose retatrutide and ramped up too quickly. I hit 3 mg titrating too fast and lost almost 30 lbs.

The funny thing? I was eating my ass off as I did not get any appetite suppression off it. The energy was unmatched and only problem was increased HR and sleep was tough.

I would look at retatrutide as a tool to use in microdoses as a way to off set side effects of AAS GH slin and aging.
You may surprise yourself at how little it takes to get results on the health markers.
 
WhiteApe

WhiteApe

Senior Member
Nov 11, 2025
169
169
I have a visceral reaction to hearing people brag about how much weight they’ve lost and how easy it is with GLP drugs.

My first thought is that if all they do is take away cravings and limit your intake, then all it takes is discipline and you’re literally bragging about being lazy and cheating.

Then I think, well shit dude, I’m on gear. That’s cheating right? Isn’t that hypocrisy at its finest? Pot -> kettle, kettle -> pot?

And then I come back around and realize that all the gear in the world doesn’t give you the dedication to show up every day, eat every meal, abstain from every vice, etc.

I don’t say anything to anyone about it. I keep it all bottled up and just pretty much hate the new skinny-fat fucks who still haven’t changed a damn thing in their life besides an injection.

I’ve always been a huge advocate for fatties taking the initiative to do ANYTHING to help themselves, like walking, cleaning up their diet incrementally, joining a gym, etc. I’ve gone out of my way to encourage people who are actually doing something real, because I mean it and I also think it’s motivating to have a big meathead quietly say “hey, you’re doing awesome, I’ve seen the progress. Keep it up brother/sister.” But this feels different to me.

This is also not meant to strafe the bodybuilding and fitness crowd using it, although I’d like to know why, Barney style. Break it down for me why Reta is better than me just eating with discipline.


Tell me why it’s different, better, the same, worse. Tell me I’m being a Karen. Hopefully someone understands where I’m coming from.
I totally understand what you’re saying but it’s also a tool that’s available so why not use it? Why is clen, whinny, and tren cool but not Reta? Because ones newer? Folks are getting on stage using Reta and not touching harsher compounds. Sounds like a win to me.

Reta also have effects past just blunting hunger. So not only are people staying away from harsher compounds they are also ditching things like metformin. Now instead of 5 drugs it’s down to 1. What’s not to like?

it’s my first time shooting for single digit body fat. Why wouldn’t I use a tool to take away a bit of hunger? It won’t take it all but might help. I’m also running super low dose, not even close to clinical dose.

the biggest win I’ve actually experienced from Reta is I’ve been able to break my addiction to alcohol. So if that’s the only thing Reta does for me, I consider it a win.
 
tommyguns2

tommyguns2

Senior Moderators
Staff Member
Dec 25, 2010
8,036
8,609
I think I understand the conundrum here. In the bodybuilding space, I see simply as one more tool in our toolbox, along with clen, DNP, intermittent fasting, and whatever else we occasionally use.

With respect to GLP1s, the general population is experiencing obesity at rates that are unprecedented. I've heard stats that over 65% of the U.S. adult population is overweight, and a higher percentage of U.S. youth are obese. The health impacts on our society and the decrease in quality of life are so great, that anything we can do to START the process of them overcoming this health condition should be considered.

I'm hearing that a decent percentage of people are re-gaining their weight after coming off the GLP1s. That clearly indicates that they haven't learned any other effective lifestyle skills to keep the weight off. Don't ditch the GLPS1, in my opinion, but incorporate more education to get these people walking or whatever, so that they feel better, and remain better over the long term.
 
J2048b

J2048b

VIP Member
Jul 2, 2012
954
618
I think people see it as a cheat because a ton of these way over weight fatties women that have never done much but live off the guvmnt… are suddenly feeling like they deserve more instead of eminem baking them a cake for their battering… P )

on a serious note a lot of people who havent used it jumped on the band wagon at first… now they are the hypocrites… ill never use this blah blah blah… until they realized they are dead ass wrong and as others have stated, these have shown to stop addictions, lessen the food noises, help obese people… BUT they also need to change habits or it wont work later

what kills me are the girls who take these and then become cunts because they feel they are better than everyone or prettier than everyone… saw a lady on Reddit… looked great, thick in all the right places… loves her now flat ass and tiny tits…. Makes no sense but will probably then go get a tit job…. Mental health is skewed and these drugs really fuck peoples perception…

my wife was on tirz in and out of the hospital non stop puking… literally dying on our bathroom floor… shitting herself while violently puking… all because she didnt listen to me, and started at 2.5 ml the doctor told her to do… had she listened…. Theres a chance i could have finally been happy and divorced by now… but nooooo she wont touch it again haha
 
WhiteApe

WhiteApe

Senior Member
Nov 11, 2025
169
169
I think I understand the conundrum here. In the bodybuilding space, I see simply as one more tool in our toolbox, along with clen, DNP, intermittent fasting, and whatever else we occasionally use.

With respect to GLP1s, the general population is experiencing obesity at rates that are unprecedented. I've heard stats that over 65% of the U.S. adult population is overweight, and a higher percentage of U.S. youth are obese. The health impacts on our society and the decrease in quality of life are so great, that anything we can do to START the process of them overcoming this health condition should be considered.

I'm hearing that a decent percentage of people are re-gaining their weight after coming off the GLP1s. That clearly indicates that they haven't learned any other effective lifestyle skills to keep the weight off. Don't ditch the GLPS1, in my opinion, but incorporate more education to get these people walking or whatever, so that they feel better, and remain better over the long term.
Great points. I would have to add that in my case I’ve been working with a nutrition coach since July. Paid for a whole year up front. I’m learning the right eating habits. It’s my first time as an adult to where I’ve been consistent in the gym. I started doing the work first. Did my first fat loss phase from 200 to 180. No drugs. No peptides. Just diet and exercise.

Now that I’ve laid some groundwork, I’m adding in tools to help. Help maintain muscle, increase mitochondria health, blunt hunger.

why take SLU or Mots C? Strenuous cardio will increase mitochondria. Don’t be lazy. Do your hit cardio. I say this tongue in cheek but it’s kind of the same as the Reta question.

but I love the fact that habits and routine was brought up as well.
 
lfod14

lfod14

Member
Jul 15, 2025
58
47
It's two sided, some of it is the appetite suppression, the other half is immediate insulin sensitivity. I use Sema, my wife uses Reta. She swears by that crap. From Sema, Tirz, and Reta, Sema puts a good beating on appetite, Tirz just shy of wipes it out, Reta is the middle of the other two, but with more weight loss shown in people. The 4-way is already floating around now, given how the others are working doesn't seem there's a huge reason to try it though.
 
IronInsanity

IronInsanity

TID Board Of Directors
May 3, 2011
3,650
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It’s still pretty similar. For the fat loss, that’s your perspective. I bet they’d say it’s still hard and takes work. The general public thinks that guys with big muscles aren’t putting in the work and owe it all to steroids. It is the pot calling the kettle black.
 
Ron OG Mouse

Ron OG Mouse

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Sep 29, 2025
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From someone who is larger even when lean. @ 5'11 215 my parents thought I was anorexic for my first show. I could look at someone who is 165 when that lean and say wtf you lazy ass can't you just eat and go to the gym to get here. Steroids are for lazy asses. But I don't because I know the dedication and effort they put in. I have lost weight with GLP1s and without GLP1s both. They are a tool that makes it easier. So I will use that tool.

With GLP1s and Test I did not need to go to the extremes that I once have and was able to keep and build muscle as I went. There was a time I would work out and do two 45 min sessions of cardio ED. Ate nothing but chicken and chicken

Not to mention the huge epidemic of fat asses in our country's. Our nation has allowed greedy corporations to push their processed foods to an unhealthy extreme. No where else are they allowed to serve this crap to the population. Places like the EU have laws forbidding the extremes we have here. To protect it's population. We need something to help combat this epidemic and I really don't care if it appears lazy.
 
SAD

SAD

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Feb 3, 2011
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It’s still pretty similar. For the fat loss, that’s your perspective. I bet they’d say it’s still hard and takes work. The general public thinks that guys with big muscles aren’t putting in the work and owe it all to steroids. It is the pot calling the kettle black.

If you take test and do nothing different, nothing much of anything happens.

If you take sema and do nothing different, you lose more weight than you never could before.

And they DO say it’s easy and takes zero work. The vast majority of the fatties are just using it instead of doing anything positive to make the change.


I’ve been reading the responses and I appreciate the input. I think what grinds my gears is the attitude that we just accept pharmaceuticals as the only resort now. If Europe keeps this from happening without the drugs, can’t we?

I’ve always been pretty anti pharma as we do it here in America. Other countries can’t and don’t advertise directly to consumers. Whereas we have commercials to try and put you on something for everything, and it’s just accepted as the go-to instead of actually healthy alternatives.

And at the end of the day, if you can’t stay on it indefinitely, then we’ll see a bunch of problems in the coming years.

Again, this is directed at the non-fitness use, not people who are adding it into a healthy regimen, although I’m still not sold on long term use or safety.
 
jhotsauce7

jhotsauce7

TID Board Of Directors
Jan 18, 2011
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If you take test and do nothing different, nothing much of anything happens.

If you take sema and do nothing different, you lose more weight than you never could before.

And they DO say it’s easy and takes zero work. The vast majority of the fatties are just using it instead of doing anything positive to make the change.


I’ve been reading the responses and I appreciate the input. I think what grinds my gears is the attitude that we just accept pharmaceuticals as the only resort now. If Europe keeps this from happening without the drugs, can’t we?

I’ve always been pretty anti pharma as we do it here in America. Other countries can’t and don’t advertise directly to consumers. Whereas we have commercials to try and put you on something for everything, and it’s just accepted as the go-to instead of actually healthy alternatives.

And at the end of the day, if you can’t stay on it indefinitely, then we’ll see a bunch of problems in the coming years.

Again, this is directed at the non-fitness use, not people who are adding it into a healthy regimen, although I’m still not sold on long term use or safety.
The difference is a huge portion of what they’re losing is muscle mass and once they stop They will gain it all back in 18 months according to a recent study.
In the bodybuilding world it’s still no magic bullet, if you wanna keep your lbm and lose fat.. so idk apples and oranges maybe.

I consider it just another tool in the toolbelt to go with good nutrition, rest and training habits (lifestyle). Nobody gets extra points for suffering more.. either in prep, or in life. Think the metabolic affects and synergy with GH for Reta are the main reasons why I’ve used it for a few months. The appetite reduction is nice for cutting but I still have an appetite.. it’s not totally gone. I can eat the correct amount of calories and hit macros without an issue 99% of the time. But I don’t really see it any different than using GH or DNP or clean/t3 etc. for what it’s worth
 
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SAD

SAD

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Feb 3, 2011
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Does the Reta itself significantly improve bloodwork?

Or is it the reduction in calories and lack of binging and reduced cravings for alcohol/fat/sugar?

That is to say, would Joe Blow have different bloodwork if he didn’t run retatrutide and instead just ate the exact same diet as his twin brother Bo, who did run retatrutide in order to maintain the diet his brother Joe did with just discipline?

I’m guessing there’s a difference, I’m just wondering how big the difference is.
 
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