I used Peptide Sciences for about six months. It did seem to take the edge off of cravings, but I did not get the pronounced appetite control that many seem to rave about. Increasing the dose seemed to have no additonal effects (ramped up to 1.5mg weekly). There is a huge Semaglutide thread over on Meso with a ton of info about vendors as well, but consensus was that PS was legit. In the end, it seemed to give me heartburn, and with only mediocre results and the price, I moved on. I'm on a low dose of Clen now, which (for now) is doing a better job.