NutNut
MuscleHead
- Jul 25, 2011
- 865
- 172
I'm not soley convinced either bro, these are just possibilities and not proven . it's possible in men for fat loss with hcg stimulating T levels and an indirect effect of androgens which inhibit the ability of some fat cells to store lipids by blocking a signal transduction pathway that normally supports adipocyte function. Also, androgens, but not estrogens, increase beta adrenergic receptors while decreasing alpha adrenergic receptors- which results in increased levels of epinephrine/ norepinephrine due to lack of alpha-2 receptor negative feedback and decreased fat accumulation due to epinephrine/ norepinephrine then acting on lipolysis-inducing beta receptors.
Looks like everyone will have to try it for them selves. I'd rather use GH lol
if anything those with low hormones is the main way it's working by increasing hormone levels if it is imo.
Those studies sertainly don't look to promising for hcg and fat loss. lol
The usual signal transduction pathway is AC–cAMP–PKA activation for HCG which in it's self has no impact on fat loss but I can see where your going with an indirect effect, my concern however is that even that should cause a difference in a double blind if the impact is noticeable. Since the idea is that HCG mimics LH and therefore causing leydig cell stimulation and as a result test production I'd think that would really only apply to those with low test (and off cycle) but we are in theory land at this point (otherwise it's going to cause natural LH production shutdown). I like to stay the course and base my conclusions on the healthy individual otherwise we will run into many scenarios.