I used to love HCG back in the day....but not sure what changed but since 2005 every type and even microdosing HCG I get nauseous and achy breaky . Includes scripted USPharm and Pregnyl as well.Unrelated.......I love me a clomid & HCG cycle. I am interested in knowing more about enclomiphene citrate.
Preliminary investigation the dosage required is not cost effective for me.
I'm not sure yet. The way to run it would be to come off after 2-4 week on hCG last two weeks of cycle and 2 weeks after. Introduce enclom after a week off and run for 4 weeks. Test 8 weeks after that. So looking at a full 12 weeks off to see if the restart took. I probably wont do that the first ime I use it. I will probably do the hCG end of cycle, 2 weeks after and 1 week after last shot add in enclom. Then at week 6 off test to see where test, LH and FSH are just to see if the drug works as advertised.Dose and duration you are planning?
Clomiphene is a mix of two isomers zuclomiphene (38%) and enclomiphene (62%). Zuclomiphene is more estrogenic, whereas enclomiphene is more anti-estrogenic, thus pure ENCL is more efficacious for hypogonadal males and raising testosterone. The only issue with these drugs is that they reduce IGF-I and blunt the GH response. The argument is that IGF-I causes cancer (although the GH/cancer association is weak and discussed in another thread) so if one raises T and decreases IGF-I, one would reduce the prostate cancer risk, also assuming T causes prostate cancer and we now know it does not. GH is a key regulator of hepatic and extra-hepatic (muscle) IGF-I production, and GH regulates myostatin production (low GH = higher myostatin = blunted muscle hypertrophy). I would like to see is a study where subjects are given T + hCG (to maintain fertility) or enclomiphene to raise T to about the same levels, then measure changes in lean/fat mass, BMD, QOL, hormones, erectile function, libido, etc of a year period time. That would really help sort this out. A combined ENCL + GH study would also be interesting.Unrelated.......I love me a clomid & HCG cycle. I am interested in knowing more about enclomiphene citrate.
Preliminary investigation the dosage required is not cost effective for me.
My insurance wouldn't cover enclomiphene w/o addtional headache AND no one in my region compounds it. I am currently on clomid 25mg/day and 25mg of exemestane EOD my total T is 807 and free is 417. I will be likely switching to either anastozole or letrozole for a better terminal half-life, therefore more stable long term blood plasma levels. For a quick cost comparison I think I'm paying about $30/month for my combo vs the $130 or so depending on the online vendor.A buddy asked about this--enclomiphene citrate. Had never heard of it before. Did a search here and it is mentioned in another TRT thread.
Anyone else tried it or know anyone who's used it? Basically, did it work very well?
Here's a link to an interesting study--
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