Definitely have noticed it. Few years ago now, I needed a break to get health markers back in check and when I did I got sciatica bad in left leg. Did physical therapy and nothing helped. 8 months later went back on cycle and it went away in probably 2 weeks of being back on. It was crazy! Surprisingly it never came back either, when I came off (true trt dose) again. And I have dropped to true trt at few times since then. I’m on just 150mg test decanoate per week right now and my back is bugging me some but no sciatica. My left knee is bugging now too which I hurt shortly before coming off my last blast. It stopped hurting but came back when I dropped to trt. I think being on a blast also increases fluid in the joints which helps with joint pain too. At least that was my theory. Something instantly changes when on. I thought I would be dealing with sciatic the rest of my life. My left hamstring had around a 40% reduction in strength when that was going on. Strength went back to normal very shortly after increasing hormones. I was honestly scared to come back off but new I had to. Stayed on longer than I should have. But to my surprise it didn’t come back. I always try to stay off (just trt) as long as I was on. I’m fairly certain it was from doing hyperextensions during the blast before I came off and the sciatica started. Was the only new exercise I had been doing. Only thing different. I already had stopped doing squats and deads because of lower back pain. I thought doing hypers would help but made things worse it seems. And It hasn’t came back since dropping them.