Apr 19, 2016 It's a "blast" dose to handle a full-blown outbreak. 4g per day for 2-3 days and then you stop. I see no need to run a daily suppression dose especially for cold sores. The typical suppression dose is 1g/day forever. That represents a much bigger insult to the liver long term than the blast dose take once every few months (or less) when you have an outnreak.