TRT and microdosing

[tommyguns2]

Microdosing TRT – The Future of Testosterone Replacement Therapy - The Men’s Health Clinic

Microdosing is the most effective way to mimic natural Testosterone levels and minimise side effects. We explain why in this article.

themenshealthclinic.co.uk

 

[Rider]

Very interesting, good post Tommy. So essentially consistent daily micro-dosing even with long acting test esters is more effective regarding stabilization.

 

[Ogre717]

I've considered this, just loading a week's worth of pins and setting them on the nightstand

 

[beefnewton]

I've been doing this since I decided to go UGL about nine or so years ago, but I use Prop. Fast forward to now, and I do two weeks of syringes at a time, but I also mix Mast P and Primo E with the Test. Has worked well enough, but I never used the longer esters on a schedule like twice a week or anything, so I don't know any different. One thing I've noticed is over the years I've had to increase my Test dose a few times. Always wondered if it was some kind of androgen resistance, increase in receptors, or what. Same result either way.. more Test.

 

[tommyguns2]

Emeric has a long thread (about 75 pages long) over at PM about 10mg test cyp ED, and how TRT levels at this dose provide excellent results. I think it affects total test, but more importantly free test in blood work.

I need to find the patience to read both this article and that long thread to better understand the "whys". But the "what" is pretty simple. I already pin GH daily with an insulin syringe. I suspect that after a month of this, I won't think too much about it.

I'm wondering if a daily application of a test base dermal would give similar results or if one key here is the daily injection of a long estered test (where C, E or U).

 

[Ogre717]

Emeric has a long thread (about 75 pages long) over at PM about 10mg test cyp ED, and how TRT levels at this dose provide excellent results. I think it affects total test, but more importantly free test in blood work.

I need to find the patience to read both this article and that long thread to better understand the "whys". But the "what" is pretty simple. I already pin GH daily with an insulin syringe. I suspect that after a month of this, I won't think too much about it.

I'm wondering if a daily application of a test base dermal would give similar results or if one key here is the daily injection of a long estered test (where C, E or U).

I think the ester mis meaningless if pinning daily. After a week or two everything should be balanced and not spiking regardless of the ester

 

[SAD]

I think the ester mis meaningless if pinning daily. After a week or two everything should be balanced and not spiking regardless of the ester

That’s not exactly what the bloodwork showed. The testogel needed twice daily administering to achieve a similar graph as the test c/e pinned just once daily.

I’ve already planned to pin my test C EOD along with the topical test base once daily, and adjust from there. Now I may increase the frequency of test C to daily and topical to twice daily (once I get my hands on it).

I ran a European test base topical about 10 years ago, for about 2 months, and I never felt or looked better (on any comparative dose of test taken IM or subQ). I definitely love the dht conversion and I think I may respond much better to topical than IM. Just me, but it was NOTICEABLE.

@tommyguns2 Thank you for this write up. That clinic sounds like an absolute winner.

 

[69nites]

I've been doing every day injects for a very long time.

Personally I like the routine and using slin pins. Anything else is a bonus.

 

[Wilson6]

I've been doing this since I decided to go UGL about nine or so years ago, but I use Prop. Fast forward to now, and I do two weeks of syringes at a time, but I also mix Mast P and Primo E with the Test. Has worked well enough, but I never used the longer esters on a schedule like twice a week or anything, so I don't know any different. One thing I've noticed is over the years I've had to increase my Test dose a few times. Always wondered if it was some kind of androgen resistance, increase in receptors, or what. Same result either way.. more Test.

What is your dosing of each? Check out some of Carruthers papers. https://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2007.00721.x

 

[beefnewton]

What is your dosing of each? Check out some of Carruthers papers. https://onlinelibrary.wiley.com/doi/10.1111/j.1743-6109.2007.00721.x

I'm up to 210mg per week of Test Prop. For the others, 140mg of Mast P and 175mg of Primo E per week. All split/injected daily. When I mentioned not doing longer esters, I only meant Test. Way back earlier in TRT, I could only manage maybe 10mg max of Test daily. I over-responded, but I was also about as out of shape as one can get and overweight. It really wasn't until 6-7 years later when I started working out that I started noticing my Test levels getting lower for my given dose (I feel best in the 800's). So my thought is my body actually needed to increase Test but couldn't (primary hypogonadism). And from that point on, I've seemed to have needed an occasional bump but also seemed to have leveled off a bit on that. For the Mast and Primo, I need to experiment with dose changes. I feel like I got more out of the Mast a few years ago. It gave a certain "hardness" to my muscles that I haven't felt in a while. The Primo was originally started as an anti-catabolic because my body loves shedding muscle, but nowadays I use it primarily to control estrogen (I cannot go beyond 175mg per week, or it will push my E2 way too low). I struggled with low E2 for years and just could never figure it out until I started seeing debates about its anti-estrogenic effects in some people.

That paper reads like a Glycomann post, except one that he dumbed down a little so I could just barely understand it.

 

[Bilter]

Years ago I had read a study where monkeys were administered testosterone, in the form of TNE, baked into cookies. They were given a cookie each morning. It proved to be an effective treatment ( I was expecting a complete failure as I always was under the impression that the TNE would be broken down in the gut). I wish I could find the study to share it.

 

[Wilson6]

I'm up to 210mg per week of Test Prop. For the others, 140mg of Mast P and 175mg of Primo E per week. All split/injected daily. When I mentioned not doing longer esters, I only meant Test. Way back earlier in TRT, I could only manage maybe 10mg max of Test daily. I over-responded, but I was also about as out of shape as one can get and overweight. It really wasn't until 6-7 years later when I started working out that I started noticing my Test levels getting lower for my given dose (I feel best in the 800's). So my thought is my body actually needed to increase Test but couldn't (primary hypogonadism). And from that point on, I've seemed to have needed an occasional bump but also seemed to have leveled off a bit on that. For the Mast and Primo, I need to experiment with dose changes. I feel like I got more out of the Mast a few years ago. It gave a certain "hardness" to my muscles that I haven't felt in a while. The Primo was originally started as an anti-catabolic because my body loves shedding muscle, but nowadays I use it primarily to control estrogen (I cannot go beyond 175mg per week, or it will push my E2 way too low). I struggled with low E2 for years and just could never figure it out until I started seeing debates about its anti-estrogenic effects in some people.

That paper reads like a Glycomann post, except one that he dumbed down a little so I could just barely understand it.

Sorry, bottom line there are a number of variables that can lead to androgen resistance, age is one.