Latest posts

Forum Statistics

Threads
27,632
Posts
542,689
Members
28,580
Latest Member
Rolanalon
What's New?

Steroids cut death rates among critically ill COVID-19 patients, major study finds

Lizard King

Lizard King

Administrator
Staff Member
Sep 9, 2010
14,550
8,020
https://www.reuters.com/article/us-...d-19-patients-major-study-finds-idUSKBN25T20D

By Kate Kelland
LONDON (Reuters) - Treating critically ill COVID-19 patients with corticosteroid drugs reduces the risk of death by 20%, an analysis of seven international trials found on Wednesday, prompting the World Health Organisation to update its advice on treatment.
The analysis - which pooled data from separate trials of low dose hydrocortisone, dexamethasone and methylprednisolone - found that steroids improve survival rates of COVID-19 patients sick enough to be in intensive care in hospital.
"This is equivalent to around 68% of (the sickest COVID-19) patients surviving after treatment with corticosteroids, compared to around 60% surviving in the absence of corticosteroids," the researchers said in a statement.

"Steroids are a cheap and readily available medication, and our analysis has confirmed that they are effective in reducing deaths amongst the people most severely affected by COVID-19," Jonathan Sterne, a professor of medical statistics and epidemiology at Britain's Bristol University who worked on the analysis, told the briefing.
He said the trials - conducted by researchers in Britain, Brazil, Canada, China, France, Spain, and the United States - gave a consistent message throughout, showing the drugs were beneficial in the sickest patients regardless of age or sex or how long patients had been ill.
The findings, published in the Journal of the American Medical Association, reinforce results that were hailed as a major breakthrough and announced in June, when dexamethasone became the first drug shown to be able to reduce death rates among severely sick COVID-19 patients.
Dexamethasone has been in widespread use in intensive care wards treating COVID-19 patients in some countries since then.
Martin Landray, a professor of medicine and epidemiology at the University of Oxford who worked on the dexamethasone trial that was a key part of the pooled analysis published on Wednesday, said the results mean doctors in hospitals across the world can safely switch to using the drugs to save lives.
CLEAR BENEFITS
"These results are clear, and instantly usable in clinical practice," he told reporters. "Among critically ill patients with COVID-19, low-dose corticosteroids...significantly reduce the risk of death."
Researchers said the benefit was shown regardless of whether patients were on ventilation at the time they started treatment. They said the WHO would update its guidelines immediately to reflect the fresh results.
Until the June findings on dexamethasone, no effective treatment had been shown to reduce death rates in patients with COVID-19, the respiratory disease caused by the new coronavirus.
More than 25 million people have been infected with COVID-19 and 856,876 have died, according to a Reuters tally.
Gilead Sciences Inc's remdesivir was authorised by United States regulators in May for use in patients with severe COVID-19 after trial data showed the antiviral drug helped shorten hospital recovery time.
Anthony Gordon, an Imperial College London professor who also worked on the analysis, said its results were good news for patients who become critically ill with COVID-19, but would not be enough to end outbreaks or ease infection control measures.
"Impressive as these results are, this is not a cure. We now have something that will help, but it is not a cure, so it's vital that we keep up all the prevention strategies."
 
DungeonDweller

DungeonDweller

VIP Member
Mar 21, 2017
1,534
1,335
Was wondering why no one was treating it with corticosteroid drugs as used with people with asthma. I guess they are, and successfully. I wonder if you can use those along with Hydroxychloroquine.
 
CFM

CFM

National Breast Implant Awareness Month Squeezer
Mar 18, 2012
2,009
1,716
So they didn't shoot test they were given prednisone. Yes, prednisone is a steroid, but not 'that kind' of steroid.
 
Lizard King

Lizard King

Administrator
Staff Member
Sep 9, 2010
14,550
8,020
Yes, prednisone greatly reducing the swelling/inflammation in lungs of asthmatics, increasing the airflow/capacity.
 
Yaya

Yaya

VIP Member
Jun 25, 2012
1,077
366
Would tren cough open up the lungs?

If yes... I'd advise stocking up on fina pellets and some fina-kits... or maybe some vegetable oil and secret solution
 
Bigtex

Bigtex

VIP Member
Aug 14, 2012
1,135
1,679
Was wondering why no one was treating it with corticosteroid drugs as used with people with asthma. I guess they are, and successfully. I wonder if you can use those along with Hydroxychloroquine.

There is a doctor in West Texas that is known for doing this treatment. He does the HCQ, Zink protocol combined with Budesonide and Clarithromycin. He prefers Clarithromycin to zpacs. The Budesonide is a corticosteroid used in a nebulizer.

My wife and I both used this particular protocol but used the zpacs instead. It takes about 15 minutes on the nebulizer to use all of the Budesonide and it is done for 1 day, morning and night. Opens the lungs. clears the inflammation quickly. The same drug is used in COPD medications but this doctor said you supersaturate the lungs much better using the nebulizer. One of our Texas congressmen also used this protocol recently.
 
Who is viewing this thread?

There are currently 0 members watching this topic

Top