Aromasin is barely any more effective at limiting estro, but the other benefits are why one would want to choose it over adex. As mentioned, it's not as harsh, has a longer half-life, and (just learned this recently) doesn't cause an estrogen rebound because of it's mechanism of action.
Why do you want to know KBD? You're sticking to your pct right?
Aromasin is barely any more effective at limiting estro, but the other benefits are why one would want to choose it over adex. As mentioned, it's not as harsh, has a longer half-life, and (just learned this recently) doesn't cause an estrogen rebound because of it's mechanism of action.
Why do you want to know KBD? You're sticking to your pct right?
I thought this as well, but after researching it I came to the conclusion that the half life or arimidex is about 3 days....while the half life of aromasin is just over 1 day. So, really aromasin is the one you need to take more often. This may be one of the biggest misconceptions I've seen in awhile.
Holy shit, I need to double check my information sources from here on out, . lol. I appreciate the correction though. Takes an honest man to clarify something that otherwise could have just gone uncorrected and unnoticed.
Aromasin is a bit stronger than anastrazole
the plasma half-lives of anastrozole (1 mg once daily), letrozole (2.5 mg once daily), and exemestane (25 mg once daily) 41-48 hours, 2-4 days, and 27 hours
With Aroma -exemestane the effects can last up to 3-4 days later after a daily dose.
exemestane as low as 2.5m ed lowers SHBG , nolva increases it by quite a bit. at that dose or higher aromasin imo is great as a part of pct to lower elevated shbg from nolva and level out aromatic protien enzymes. High aromatse levels can stay elevated for quite sometime leading to estrogen rebound ounce your off the nova/clomid. good reason to taper those two over a period for pct if you don't add aromasin in at the end to level out aromatase.
Exemestane plasma levels increased by approximately 40% when taken with food, preferably high in fat for best absorption.
supression starts at 5-mg daily dose of exemestane, with a maximum suppression of at least 85% with 25mg ed. maximal suppression of circulating estrogens occurrs about 2 to 3 days after dosing.
An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane
Buzdar AU, Robertson JF, Eiermann W, Nabholtz JM.
Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center,
Aromasin is a bit stronger than anastrazole
the plasma half-lives of anastrozole (1 mg once daily), letrozole (2.5 mg once daily), and exemestane (25 mg once daily) 41-48 hours, 2-4 days, and 27 hours
With Aroma -exemestane the effects can last up to 3-4 days later after a daily dose.
exemestane as low as 2.5m ed lowers SHBG , nolva increases it by quite a bit. at that dose or higher aromasin imo is great as a part of pct to lower elevated shbg from nolva and level out aromatic protien enzymes. High aromatse levels can stay elevated for quite sometime leading to estrogen rebound once your off the nova/clomid. good reason to taper those two over a period for pct if you don't add aromasin in at the end to level out aromatase.
Exemestane plasma levels increased by approximately 40% when taken with food, preferably high in fat for best absorption.
supression starts at 5-mg daily dose of exemestane, with a maximum suppression of at least 85% with 25mg ed. maximal suppression of circulating estrogens occurrs about 2 to 3 days after dosing.
An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane
Buzdar AU, Robertson JF, Eiermann W, Nabholtz JM.
Department of Breast Medical Oncology, The University of Texas M. D. Anderson Cancer Center,
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