I get no pain but I don't grab the bar in a full reverse grip, more so my index finder is pointing along the bar, if that makes sense. I get no wrist pain from it that way. I also do it close grip with a full grip for tri's.
Physiologically I see no reason why the chest can't be recruited, the movement of the humerous relative to the body is what effects pec recruitment, and the movement is equal to if not greater than flat bench.
Happy if anyone knows a reason against what I said though, also happy I finally remember my password after like 6 months