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Nolvadex Hair Regrowth?

KBD

KBD

I Look Good...
Sep 13, 2010
2,312
107
#1
Drug Wakes Dormant Hair Follicles

You're not bald-- you just have a lot of dormant hair follicles that
haven't been awakened yet. University of Michigan Medical Center
researchers found that rubbing a cream containing the cancer-fighting
drug Tamoxifen (trade name Novaldex) on rats just one time activated
dormant hair follicles and increased hair growth. Applying the drug
repeatedly caused the rats to produce too much hair. The treatment
worked only in mice that were genetically altered to create baldness.
Bald men have dormant follicles-- healthy, but not producing hair.
This research is exciting because it shows we may be able to wake up
these dormant follicles. (Genes Dev., 17: 1219-1224, 2003)


Genes Dev. 2003 May 15;17(10):1219-24.

Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.

Van Mater D, Kolligs FT, Dlugosz AA, Fearon ER.

Departments of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan 48109, USA.

Wnts have key roles in many developmental processes, including hair follicle growth and differentiation. Stabilization of beta-catenin is essential in the canonical Wnt signaling pathway. We developed transgenic mice expressing a regulated form of beta-catenin in the skin. Chronic activation of beta-catenin in resting (telogen) hair follicles resulted in changes consistent with induction of an exaggerated, aberrant growth phase (anagen). Transient activation of beta-catenin produced a normal anagen. Our data lend strong support to the notion that a Wnt/beta-catenin signal operating on hair follicle precursor cells serves as a crucial proximal signal for the telogen-anagen transition.
 
Get Some

Get Some

MuscleHead
Sep 9, 2010
3,441
643
#2
Figures the first stufy you would ever post is about hair regrowth, lol
 
KBD

KBD

I Look Good...
Sep 13, 2010
2,312
107
#3
Figures the first stufy you would ever post is about hair regrowth, lol
Hahaha u know me too well..

Sounds interesting thought. Although i dont think i want to take the chance of rubbing nolvadex on my head lol.
 
Lizard King

Lizard King

Administrator
Staff Member
Sep 9, 2010
11,588
3,412
#4
I assume you are compounding the cream yourself at this very minute. Would be good for a lot of baldies if this worked.
 
Get Some

Get Some

MuscleHead
Sep 9, 2010
3,441
643
#5
Hahaha u know me too well..

Sounds interesting thought. Although i dont think i want to take the chance of rubbing nolvadex on my head lol.
Why don't you repost that study on Meso except change "nolvadex" to "DNP Powder" and tell BR and Millard to leave the thread alone, lol
 
jdjack

jdjack

MuscleHead
Sep 22, 2010
568
32
#7
Why don't you repost that study on Meso except change "nolvadex" to "DNP Powder" and tell BR and Millard to leave the thread alone, lol
LMAO well wouldn't someone notice the 'change' when they were compounding it.
 
ozzy69

ozzy69

MuscleHead
Apr 5, 2011
488
54
#8
so rub some nolvadex on my bald spot and the hair regrows? gotta call this bullshit...once the follicle "dies" and stops producing hair its game over for that spot
 
KBD

KBD

I Look Good...
Sep 13, 2010
2,312
107
#9
so rub some nolvadex on my bald spot and the hair regrows? gotta call this bullshit...once the follicle "dies" and stops producing hair its game over for that spot
Not necessarily, look at rogaine. Try rubbing some tamox on your head lol.
 
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