Jan 15, 2011 Remeron (mirtazapine) from Organon is a new-age anti-depressant that comes in 15mg and 30mg tablets. Remeron is widely reported to have shown to have an acute inhibiting effect on cortisol secretion in healthy subjects. Apparently, mirtazapine rapidly attenuates HPA axis hyperactivity via direct pharmaco-endocrinological effects. See the following link for the evidence: Mirtazapine ( Remeron ) growth hormone, prolactin, and cortisol secretion Does the data reflected in the above link suggest Remeron could function as an effective anti-catabolic? Furthermore, has anyone used Remeron effectively for this purpose?