HRT & Prostrate Cancer benefits

[graniteman]

Found this article, another bump for Test!


Testosterone Replacement Therapy & Prostate Cancer Detection

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Researchers in the United Kingdom recently completed an updated audit of the prostate safety data from the UK Androgen Study (UKAS). This was a long-term multicenter investigation into the treatment of age-related testosterone deficiency (hypogonadism) in men. The data was taken from a total of 1,365 men under treatment, with a mean age of 55 years (ranging from 28 to 87). The subjects were taking popular HRT medications including Testogel (transdermal testosterone), Restandol (oral testosterone undecanoate), mesterolone (Proviron), and testosterone pellet implants for up to 20 years. Fourteen cases of prostate cancer were diagnosed during the study, an average of 1 case every 212 treatment years. This was determined to be the same rate as expected for the general population.

Testosterone replacement therapy had no statistically significant effect on PSA levels or the likelihood of a positive cancer diagnosis in this study. The researchers here made an additional conclusion in this study, however. While hormone therapy did not influence the rate of cancer in these men, it did have a secondary benefit. By placing these men in the regular care of physicians, including periodic prostate examinations, detection of the disease was earlier than expected (mean 6.3 years). In all 14 cases, the cancers appeared to be localized and suitable for removal. The paper closes by suggesting that the monitoring that comes with male HRT may improve prostate cancer detection and treatment rates. This is worth considering whenever physicians and patients discuss the potential risks and benefits of

 

[midevil]

Good article! Keep in mind doctor prescribed trt is hormone therapy that brings a person with low test back into the normal range. Dr's start with a particular dose and test each person to find the optimal dosage required to get into the window of what would be considered normal range. The study makes perfect sense. Why would trt be any different then a man that has normal levels of test? It seems as basic as common sense.

HOWEVER, if this study were be performed on men using higher doses of test thus elevating test levels dramatically what would the results show?

Elevated test levels are believed to cause prostate cancer in men by the medical community. That's why the disclosures are heard on trt commercials and small print disclosures at the bottom of printed adsvertisments.

 

[Littleguy]

"HOWEVER, if this study were be performed on men using higher doses of test thus elevating test levels dramatically what would the results show?

Elevated test levels are believed to cause prostate cancer in men by the medical community. That's why the disclosures are heard on trt commercials and small print disclosures at the bottom of printed adsvertisments."

Exactly Middy, yes test is GREAT but we cannot pretend that more is better for our health in order to justify the use.
Thanks for posting

 

[crowman]

Great post. Ill have to dig up the article where it states Low T actually increases your risk of prostate cancer. I believe it was the correlation between low T and elevated estrogen that increased the risk thus if you can be treated hormonally with Testosterone to keep your number optimized it lowers/ reduces the risk of Prostate cancer. We actually have several patients who had prostate cancer in the past we treat and it has caused 0 issues on the negative end. One of them is actually my father.

 

[graniteman]

Great post. Ill have to dig up the article where it states Low T actually increases your risk of prostate cancer. I believe it was the correlation between low T and elevated estrogen that increased the risk thus if you can be treated hormonally with Testosterone to keep your number optimized it lowers/ reduces the risk of Prostate cancer. We actually have several patients who had prostate cancer in the past we treat and it has caused 0 issues on the negative end. One of them is actually my father.

This was my thought crowman, If we tend to get prostrate and heart\circulatory issues as we age and our test levels steadily drop , to me a knucklehead with no medical sense it seems they have something in common. I think the issue you raise with cancer survivors or prone to it , keeps many from trying hrt.
Look forward to reading more Crowman
Respect
Gman

 

[midevil]

Great post. Ill have to dig up the article where it states Low T actually increases your risk of prostate cancer. I believe it was the correlation between low T and elevated estrogen that increased the risk thus if you can be treated hormonally with Testosterone to keep your number optimized it lowers/ reduces the risk of Prostate cancer. We actually have several patients who had prostate cancer in the past we treat and it has caused 0 issues on the negative end. One of them is actually my father.

funny all of the trt adds always state "not recommended for those diagnosed with enlarged prostate, have been diagnosed or have had prostate cancer".

When I went through the whole cancer deal I was informed more then once that testosterone is the main cause of cancer...not estrogen.

It's all very complicated ..even to a person like myself that was treated for the disease.

 

[midevil]

hey buddy... thanks good to see you!

 

[graniteman]

There is no conclusive or clinical proof that testosterone causes cancer. Some researchers believe it increases the rate of cancer if you already have it, but there is no conclusive evidence either way. I just read a Harvard clip, may be the one crowman is talking about, that says low T may be a cause. Besides how many times have Doctors told us something is killing us and a year later recant ? Glad you're well midevil
Respect

 

[crowman]

There is no conclusive or clinical proof that testosterone causes cancer. Some researchers believe it increases the rate of cancer if you already have it, but there is no conclusive evidence either way. I just read a Harvard clip, may be the one crowman is talking about, that says low T may be a cause. Besides how many times have Doctors told us something is killing us and a year later recant ? Glad you're well midevil
Respect

exactly there is no proof at all linking it to cancer. Some doctors say if you you already have cancer it could be like adding fertilizer to a weed but again there is no conclusive evidence. There is however studys popping up showing a link between Low T and cancer or other issues.

 

[graniteman]

^^^It's like I was saying crowman, I'm no medical smart guy but it makes sense to this guy that if as you age and your T levels drop you develope prostrate cancer, heart\cardio vascular troubles that increasin T levels could help.
respect
gman

 

[M-Rods]

thnaks for the article, good read, I'm on my 4th shot tomorrow , the more info the better

 

[midevil]

exactly there is no proof at all linking it to cancer. Some doctors say if you you already have cancer it could be like adding fertilizer to a weed but again there is no conclusive evidence. There is however studys popping up showing a link between Low T and cancer or other issues.

I'm on self prescibed trt... and a survivor (for now). My doc would not consider me a candidate for trt when I asked because of my cancer history. you see, I have real life experience...not some article on the net..

Please post an article that you've found.. I'm very interested in reading it for obvious reasons.