Finasteride was the first one in my crosshairs. As it turned out, the overall cumulative incidence of depressive symptoms with and without finasteride was 3.33% versus 2.54%. A meta-analysis of random effects yielded an odds ratio of 2.14. In addition, the risk of suicidal ideation or behavior was higher with finasteride compared with no finasteride (21.2% vs. 14.0%), and the risk of persistent sexual dysfunction was high (60.1%). Therefore, I believe in being wary of this drug to avoid more negativity. Use a better medication instead. For example, agomelatine. Why would I use a antidepressant for DHT blocking and hair growth ? Do you know what we are talking about here?