EOD injections makes for less pins which equals less scar tissue. The benefits of injecting ED would be:
1. Levels stay pretty constant and in most cases, side effects are reduced
2. Less overall oil is injected into each muscle, lessening the post injection/next day soreness (especially with these short esters)
Disadvantages:
1. You should have at least 8 different spots if you're pinning ED. With EOD injects that number can be reduced to only 4.
2.You don't get a "spike" in levels to use to your advantage. With EOD injects, your levels will spike 18-36 hours after injection (depending on acetate or propionate ester). With EOD injections, you can inject in the late morning on Monday and expect your levels to be at peak concentration the same time the next day through late afternoon. Shceduling injects to your advantage can greatly increase chances of better pumps while working out and a better sleep pattern.
Tren can wreak havoc on your sleeping habits, so personally I choose to go EOD and plan the injections to maximize levels as far as possible from when I will be sleeping.