Coming off an Anti-E in a 60 yr old female BCa survivor

[Wilson6]

One of my female clients is a BCa survivor, cleared the 5 yr mark and was allowed to stop her anastrozole 6 mo ago. She is 60, I started training her right after her surgery. Sent her to Dr Glaser in Dayton OH where she started T with anastrozole pellets 3 yrs ago. She was about to quit the AI back then bc the side effects were terrible despite warnings from her oncologist. Her total T with pellet now ranges from about 600 ng/dl about 4 weeks after the pellet to around 250 ng/dl about 2 weeks before the next one (8-10 wks), so probably near 800 right after the pellet implant to about 200 just before. With the AI her E2 < 5 pg/ml, undetectable. The T + A resolved most of her menopausal Sx and sides of the AI with the exception of chronic wrist pain. The addition of T made dramatic changes in body comp (alot of muscle and 12% BF year round, esp in the legs and glutes). Glaser told her it would take 4 mo to start noticing life without an AI as the residual pellet lasts quite a while and very little ANAS is needed to crush E2. Over the past 2 months (now at 6 mo post AI) her wrist pain is gone, joints overall feel better, skin looks like she's 20, she has leaned out further and is harder and more muscular, has more energy and better mental clarity. She has changed nothing else (diet, training, etc.) other than drop the AI. E2 is slowly rising now from the aromatization of her T. Her Onco was opposed to the T the whole time. All her checkups have been good. Observational, but clearly she's doing better without the AI. The idea that she'd get fat, blow up with water, etc. simply is not happening with higher E2, in fact just the opposite. Something to think about.