dr jim
MuscleHead
- Apr 7, 2014
- 785
- 168
Agreed XXL but what I've a problem with is Sallies protocol uses Tamoxifen as Clomid is tapered. Why? Well as I understand it, the Clomid is started first because it "sensitizes" the LH receptor to the effects of GnRH. While that seems accurate based on RAT literature I'm familiar with, why oh why is a LESS EFFECTIVE effective SERM like Tamo used to "finish the job". Why isn't Clomid simply continued to complete PCT.
Furthermore the literature is far from convincing regarding the use of Tamo for PCT because in some RAT and a couple human (breast CA trials) Tamo was noted to LOWER LH levels.
For these reasons I've never been convinced TWO SERMS are better than one since the former only seems to COMPLICATE a relatively uncomplicated process, called PCT.
Finally as I mentioned earlier and XXL re-emphasized the organ tissue itself has a MAJOR influence on whether any SERM is an E-2 agonist or antagonists.
Jim
Furthermore the literature is far from convincing regarding the use of Tamo for PCT because in some RAT and a couple human (breast CA trials) Tamo was noted to LOWER LH levels.
For these reasons I've never been convinced TWO SERMS are better than one since the former only seems to COMPLICATE a relatively uncomplicated process, called PCT.
Finally as I mentioned earlier and XXL re-emphasized the organ tissue itself has a MAJOR influence on whether any SERM is an E-2 agonist or antagonists.
Jim