Anti-Aging Thread

[Ron OG Mouse]

https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00608-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2666379125006081%3Fshowall%3Dtrue

New study showing NAD+ prevents and reverses alzheimers in mouse models.

Too bad I will forget about this in 15 min.

 

[jhotsauce7]

Too bad I will forget about this in 15 min.

I read this and it was very interesting that supplementing NAD+ wasn’t the factor but rebalancing homeostasis of NAD+ at the cellular level reversed the impairment. Seems like a huge discovery… hope they are able to advance the research to clinical trials at some point. Alzheimers/dementia are terrible things to go through with family members.. from first hand experience

 

[jipped genes]

Great read, i take NAD+.

 

[Bigtex]

Very interesting. My mom has dementia and it is horrible.

I feel your pain @jipped genes I am going through the same thing with my mother. She is now in end-stage dementia. Paranoia, hallucinations, memory loss, etc. We are paying a fortune for 24-hour caregivers, and now we have started the hospice phase. It is also mentally and emotionally draining to my wife and I trying to take care of all that comes with this. I have had to completely take over my mom's financial obligations. Good luck to you, and if you need to just talk to someone with the same problem, let me know. I know it is hard.

 

[jhotsauce7]

I feel your pain @jipped genes I am going through the same thing with my mother. She is now in end-stage dementia. Paranoia, hallucinations, memory loss, etc. We are paying a fortune for 24-hour caregivers, and now we have started the hospice phase. It is also mentally and emotionally draining to my wife and I trying to take care of all that comes with this. I have had to completely take over my mom's financial obligations. Good luck to you, and if you need to just talk to someone with the same problem, let me know. I know it is hard.

Same story with my father. Can no longer walk or feed himself.. bed ridden and receiving hospice care.

 

[Cohiba]

I feel your pain @jipped genes I am going through the same thing with my mother. She is now in end-stage dementia. Paranoia, hallucinations, memory loss, etc. We are paying a fortune for 24-hour caregivers, and now we have started the hospice phase. It is also mentally and emotionally draining to my wife and I trying to take care of all that comes with this. I have had to completely take over my mom's financial obligations. Good luck to you, and if you need to just talk to someone with the same problem, let me know. I know it is hard.

Same story with my father. Can no longer walk or feed himself.. bed ridden and receiving hospice care.

My mom has it too. Both of my grandmother's had it, and one grandfather. It scares the shit out of me. That's one reason I follow the research on it so closely.

 

[Bigtex]

My mom has it too. Both of my grandmother's had it, and one grandfather. It scares the shit out of me. That's one reason I follow the research on it so closely.

Trust me, I completely understand. I have never had to deal with something like this. I wish you the best in dealing with this.

 

[Bigtex]

Same story with my father. Can no longer walk or feed himself.. bed ridden and receiving hospice care.

DAMN! Sorry to hear this. Just yesterday I spent most of my day getting DNR paperwork signed and notarized. It has taken 5 days to get hospice involved. I am constantly having to find ways to pay people who are helping. We live about 300 miles away, so it is very difficult to manage everything on the phone and computer. I call my mom because I feel guilty, and then feel worse after I talk to her because she makes no sense at all. She imagines people are sitting in her house and have their cars in the garage. She tells me they have taken everything in the house, and her caretaker tells me the opposite. Bro, I had to give permission for the doctors to give her a medication that will cause some of the hallucinations, paranoia, and aggressiveness, but in turn, it may shorten her life. So I have to deal with providing her comfort over a longer life of living hell. She already has a will stating she does not want to be kept alive and just die naturally. I am a pretty hardened guy who has seen a lot, and this is hard for me to deal with. Good luck to you. Hell, maybe we all need a frigging support group here.

 

[jipped genes]

I feel your pain @jipped genes I am going through the same thing with my mother. She is now in end-stage dementia. Paranoia, hallucinations, memory loss, etc. We are paying a fortune for 24-hour caregivers, and now we have started the hospice phase. It is also mentally and emotionally draining to my wife and I trying to take care of all that comes with this. I have had to completely take over my mom's financial obligations. Good luck to you, and if you need to just talk to someone with the same problem, let me know. I know it is hard.

Thanks bro. I am sorry to hear that about your mom. Me my dad and my sis split the cost of home health care and support. I know it will just cost more to come.

To all folk who have loved ones effected by dementia or Alzheimer's I have the greatest sympathy for you.