Oct 4, 2010 ALDACTONE Substance: spironolactone Remark: International, many different compounds bearing the substance spironolactone is accessible. Hence Due to restricted space they're not listed here. Aldactone is a diuretic and lies within the subgroup of potassium sparing diuretic drugs. Aldactone is an aldosterone antagonist. Aldactone regulates the body's own internal secretion, aldosterone, which speeds up the excretion of potassium and reduces the excretion of sodium and water. Simplified, aldosterone influences the endogenous water housing. The higher the aldosterone degree, the further water is stored in the body. The usage of Aldactone ensues in a substantial decrease in the aldosterone level so that an inflated excretion of sodium and water happens whilst, at the same time, potassium is resorbed. This likewise explains why Aldactone is called a potassium sparing diuretic as it doesn't induce a loss of potassium such as thiazides and furosemides (lasix) do. Athletes should stringently observe that during the use of Aldactone no other potassium is consumed since this would stimulate a life threatening increase in the blood serum potassium levels. Potassium sparing diuretics bear relatively low diuretic results so that Aldactone may be known as a modest diuretic. It is newsworthy to note that Aldactone is as well an antiandrogen because it cuts down the androgen levels. Female athletes capitalize on this feature by utilizing it to reduce the masculinization symptoms associated with steroid hormone treatment or the symptoms after a steroid cycle. For this intent Aldactone is commonly taken each day for ten to fourteen days, typically in a dose of 50 mg/day. In males this could result in troubles as the ratio of the androgen level to the estrogen level alters in favor of the latter. Hence, usual side effects in adult male* include pain in or around the nipples and breast puffiness (gynecomastia). Bodybuilders utilize Aldactone nearly only on the last week prior to a contest. Because this causes neither a striking nor an directly discernible draining result, it is generally taken over a 5 or 6 day peroid in a dose of two tabs of 50 mg every day. Both men and women athletes take it. The primary problems in males comprises of gynecomastia and potential impotence. Additional side effects can be low blood pressure, muscle spasm*, dizziness, gi, vomiting, abnormal pulse rate, and tiredness. Aldactone by Boehringer Mannheim of FRG is oftentimes found on the black market. A box carries 50 dragees of 50 mg each and is approx. $30 on the black market. On that point are presently no Aldactone counterfeits available.