5-amino-1MQ

[Wilson6]

Has anyone tried 5-amino-1MQ on their lab rat, a nicotinamide N-methyltransferase inhibitor? Either oral or sc? Very interesting small molecule.

 

[BackAtIt]

I had never even heard of it?....It does have some INTERESTING facets!....I would be curious to hear form those who have tried it as well?!....

"5-amino-1MQ has been shown to reduce the production of the enzyme nicotinamide N-methyltransferase
(NNMT),a regulator of energy homeostasis in adipose tissue (a type of fat used for energy storage). This mechanism could
shrink white adipose tissue and dramatically reduce weight without the need for limiting calorie intake. "

5-amino-1MQ - Genemedics

Obesity may significantly impact one’s quality of life, as it can negatively affect independent movement and exercise. While this condition can cause physical and emotional problems, it can also increase one’s risk for deadly diseases such as heart problems, diabetes, cancer, stroke, and...

www.genemedics.com

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[Intel.Imperitive]

Anyone have any experience with this?

 

[Wilson6]

The Mrs has a bottle from Peptide Sciences in the fridge. Has not tried it yet. It is pricey $250 a bottle. Sometime later this year, will update.

 

[Type-IIx]

Never heard of it until now! I'm reading about some interesting results (potent NNMT inhibitor, low IC50) with evidence of accelerated muscle regeneration in aged mice (sarcopenic model); reduced body weight and WAT in diet-induced obese mice; in vitro evidence of potential antiproliferative effects (potentially relevant in muscle degeneration, tissue adhesions, certain neoplasms).

 

[MR. BMJ]

Yea, same as the others W6, I had never heard of it until you mentioned it here, at least i don't think I have. Let us know how it goes!

 

[Intel.Imperitive]

Never heard of it until now! I'm reading about some interesting results (potent NNMT inhibitor, low IC50) with evidence of accelerated muscle regeneration in aged mice (sarcopenic model); reduced body weight and WAT in diet-induced obese mice; in vitro evidence of potential antiproliferative effects (potentially relevant in muscle degeneration, tissue adhesions, certain neoplasms).

Science bro.