How much protein are you consuming daily? Are you well hydrated and keeping an eye on BP? It may or may not have to do with gear, more likely dietary intake and training. Best time/way to check labs is take your protein intake down for a few days, no lifting for a week or eccentric exercise, be well hydrated. Then retest. Those values are not that high, but keep an eye on the trend. Exercise/muscle damage can raise ALT and AST, high protein intake BUN, creatinine. Watch the clen and BP. Much has been said recently about enlarged hearts and AAS, yes they contribute in higher doses, IMO keep BP < 120/80, I believe use of stimulants and not controlling BP enhances the negative affects on renal and cardiac function. Just my non-medical opinion. What was the dosing of MAST and VAR, how long on clen and have you been watching BP?
IMO keep BP < 120/80, I believe use of stimulants and not controlling BP enhances the negative affects on renal and cardiac function. Just my non-medical opinion.
Plenty of great advice already give but I will throw this into the mix since I just had to . . .
Thank you so much for this explanation it makes so much sense my trainer has said much along the same lines as well as my doc i will monitor going forward and re test ...might even try to get the cystane c test in at some point.Plenty of great advice already give but I will throw this into the mix since I just had to go over this with my cardiologist who got excited over my blood tests.
#1. Does resistance training and muscle mass have an effect
Creatinine is a substance that comes from the catabolism of creatine phosphate. Creatine is combined with phosphate to produce phosphocreatine, stored in skeletal muscle which is a precursor to adenosine triphosphate (ATP) which is used to produce energy for short duration high intensity muscle contractions. Thus, athletes involved in resistance training are more likely to have a blood creatinine level that is higher than usual. So not only does exercise play a part but muscle mass does as well. " Serum and urinary creatinine correlated significantly with body weight, but the level of correlation with lean mass was even greater. "
Baxmann AC, Ahmed MS, Marques NC, Menon VB, Pereira AB, Kirsztajn GM, Heilberg IP. Influence of muscle mass and physical activity on serum and urinary creatinine and serum cystatin C. Clin J Am Soc Nephrol. 2008 Mar;3(2):348-54. doi: 10.2215/CJN.02870707. Epub 2008 Jan 30. PMID: 18235143; PMCID: PMC2390952.
#2. Are you taking creatine supplement.
The unused creatine that’s not used as energy in the muscle gets converted into creatinine, a waste product. This will give you a false high on the test.
Williamson L, New D. How the use of creatine supplements can elevate serum creatinine in the absence of underlying kidney pathology. BMJ Case Rep. 2014 Sep 19;2014:bcr2014204754. doi: 10.1136/bcr-2014-204754. PMID: 25239988; PMCID: PMC4170516.
#3. Hight protein diets.
An increase in serum creatinine can result from increased ingestion of cooked meat (which contains creatinine converted from creatine by the heat from cooking) or increased intake of protein. Again, this high reading is not indictive of underlying kidney issues.
Samra, M., & Abcar, A. C. (2012). False estimates of elevated creatinine. The Permanente journal, 16(2), 51–52. https://doi.org/10.7812/tpp/11-121
eGFR
The eGFR test measures the level of creatinine in the blood and uses the result in a formula to calculate a number that reflects how well the kidneys are functioning, So if the levels of creatine in the blood are high from one of the above, you estimate GFR will also be high but that again does not mean your kidney function is decreased. Note the conclusion from the Baxman et al (2008) study:
Conclusions: Cystatin C may represent a more adequate alternative to assess renal function in individuals with higher muscle mass when mild kidney impairment is suspected.
Here is my last blood work
BUN - 17 (8-23)
Creatinine - 1/32 (0.70 - 1.20)
eGRF - 57 (mild to moderate decreased)
You and your comprehensive posts are really getting aggravating. If I wanted that shit I could go to an up-to-date medical pro. Failing that, I guess I can just come here .......
Was your Cardiologist happily excited, or, not so much?
You lost me there, bro.
You lost me there, bro.
Lol I was trying to make a joke about taking time off from the gym. If my numbers are caused by my physical exercise then I consider the results of the test a test of my physical exercise, not of my kidneys. I could be wrong but it lets me sleep better at night.
There are currently 0 members watching this topic