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Thread: General half life times

  1. #1
    VIP GreatGunz's Avatar
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    General half life times

    I borrowed this did not write it!

    *Note: The determined half-lives are only estimations. After performing a PCT calculation, an error margin of a few days should be considered. If you have any information that may be of aid to us, feel free to email us!
    Propionate: 2 days
    Reasoning: From analyzing graphs we determined that total testosterone levels began their drop 24 h after a single injection of 50mg testosterone propionate (1). Further analysis discovered levels were halved approximately 2 days after injection, and so that is the estimated half-life of the propionate ester.
    Phenylpropionate: 3 days
    Reasoning: Data revealed nandrolone phenylpropionate to have a little bit longer of a half-life than that of propionate (2). Although there have not been many studies done using the ester, it's estimated half-life is 3 days.
    Isocaproate: 5 days
    Reasoning: With a shorter ester than that of enanthate and longer than that of phenylpropionate, the isocaproate half-life is rougly estimated to have a 5 day half-life. This is based on the carbon composition of the ester alone as there exists very little known studies on this ester.
    Enanthate: 7 days
    Reasoning: From analyzing many graphs and data tables concerning the half-lives of testosterone enanthate(1, 4, 5), it was concluded that the half-life was measured to be about 7 days. We noted that weekly injections of 200mg TE resulted in a continual rise in total testosterone levels until it plateaued at 12 weeks (3). The total testosterone levels between the 8th and 12th week were not significantly different signifying that an estimated half-life of 7 days properly fit the calculated predictions for testosterone levels.
    Cypionate: 7 days
    Reasoning: Differing from enanthate by only 1 carbon atom, the cypionate ester has no noticeable changes in half-life from enanthate (1). Thus it shares the same, 7 days.
    Decanoate: 9.5 days
    Reasoning: Being 3 carbon atoms longer, this ester should have an extended half-life over enanthate. This is shown evidently in studies done on single-shot injections of Nandrolone Decanoate (3). The half-life varied from 7-12 days leaning more towards 12 days depending on injection site. We took the average of that which was 9.5.
    Undecanoate: 34 days
    Reasoning: From detailed graphs and also clinically calculated half-lifes in (1), the estimated half-life of the undecanoate is an impressive 34 days. Definitely not an ester to use for short cycles.


  2. #2
    VIP Member Get Some's Avatar
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    Re: General half life times

    The most interesting thing about half lives and peak plasma levels is that according to a few studies I've seen, the numbers actually depend on WHERE you are injecting. Nandrolone Decanoate injected in the glutes resulted in a higher peak plasma level than the same amount injected into the deltoid. I wish I still had that study.... I'll look for it.

  3. #3
    Weasel Hunting Moderator SHINE's Avatar
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    Re: General half life times

    Quote Originally Posted by greatgunz View Post
    I borrowed this did not write it!

    *Note: The determined half-lives are only estimations. After performing a PCT calculation, an error margin of a few days should be considered. If you have any information that may be of aid to us, feel free to email us!
    Propionate: 2 days
    Reasoning: From analyzing graphs we determined that total testosterone levels began their drop 24 h after a single injection of 50mg testosterone propionate (1). Further analysis discovered levels were halved approximately 2 days after injection, and so that is the estimated half-life of the propionate ester.
    Phenylpropionate: 3 days
    Reasoning: Data revealed nandrolone phenylpropionate to have a little bit longer of a half-life than that of propionate (2). Although there have not been many studies done using the ester, it's estimated half-life is 3 days.
    Isocaproate: 5 days
    Reasoning: With a shorter ester than that of enanthate and longer than that of phenylpropionate, the isocaproate half-life is rougly estimated to have a 5 day half-life. This is based on the carbon composition of the ester alone as there exists very little known studies on this ester.
    Enanthate: 7 days
    Reasoning: From analyzing many graphs and data tables concerning the half-lives of testosterone enanthate(1, 4, 5), it was concluded that the half-life was measured to be about 7 days. We noted that weekly injections of 200mg TE resulted in a continual rise in total testosterone levels until it plateaued at 12 weeks (3). The total testosterone levels between the 8th and 12th week were not significantly different signifying that an estimated half-life of 7 days properly fit the calculated predictions for testosterone levels.
    Cypionate: 7 days
    Reasoning: Differing from enanthate by only 1 carbon atom, the cypionate ester has no noticeable changes in half-life from enanthate (1). Thus it shares the same, 7 days.
    Decanoate: 9.5 days
    Reasoning: Being 3 carbon atoms longer, this ester should have an extended half-life over enanthate. This is shown evidently in studies done on single-shot injections of Nandrolone Decanoate (3). The half-life varied from 7-12 days leaning more towards 12 days depending on injection site. We took the average of that which was 9.5.
    Undecanoate: 34 days
    Reasoning: From detailed graphs and also clinically calculated half-lifes in (1), the estimated half-life of the undecanoate is an impressive 34 days. Definitely not an ester to use for short cycles.
    Good job Gunz! Those are realy good examples of true half-lives of varying esters taken from clinical studies. And true the half-lives although acurate for the people of those studies done with testing should be considered an estimate. Everyone does metabolize esters at different rates, (biochemical individuality) as well as other factors like Exercise, site of injection, proper injection technique (not going deep enuff will alow the depot to escape in the facia slowing release/absorption) scar tissue build up, and also the vehicle/carrier used to carry the hormone. Example below showing the half-life of test undecanoate in castor oil and Tea seed oil. Castor oil extended the half-life over 10 days of tea seed oil.

    Intramuscular injection of testosterone undecanoat... [Eur J Endocrinol. 1999] - PubMed result
    castor oil preparation had a longer half-life than TU in tea seed oil (33.9+/-4.9 vs 20.9+/-6.0 days (mean pm S.E.M.)).
    Last edited by SHINE; 07-20-2011 at 05:35 PM.

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    Weasel Hunting Moderator SHINE's Avatar
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    Re: General half life times

    Quote Originally Posted by Get Some View Post
    The most interesting thing about half lives and peak plasma levels is that according to a few studies I've seen, the numbers actually depend on WHERE you are injecting. Nandrolone Decanoate injected in the glutes resulted in a higher peak plasma level than the same amount injected into the deltoid. I wish I still had that study.... I'll look for it.

    This one is a bit easier to read than the minto, same study. Excellent study of decanoate and phenlypropionate esters.

    http://jpet.aspetjournals.org/content/281/1/93.full.pdf
    Last edited by SHINE; 07-20-2011 at 05:33 PM.

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