HCG and Spermatogenesis

Discussion in 'PCT - Post Cycle Therapy and Anti-E's' started by SHINE, Jan 28, 2011.

  1. SHINE

    SHINE Fallen Member

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    HCG and Spermatogenesis
    Interesting article here about HCG ability of stimulating spermatogenesis. These guys apparently found that in patients that went hypogonadal after puberty, HCG was 100% effective in stimulating spermatogenesis, although we are talking about a small sample size (6). In the ones that went hypogonadal during puberty, HMG was required. The ones that had a testicle missing from the scrotum on top of that were in trouble though...

    Maybe good news to anyone on HRT trying to knock the old lady up lol.


    Stimulation of Spermatogenesis by Gonadotropins in Men with Hypogonadotropic Hypogonadism

    David M. Finkel, M.D., Jennifer L. Phillips, B.A., and Peter J. Snyder, M.D.

    N Engl J Med 1985; 313:651-655September 12, 1985
    Abstract

    We evaluated the efficacy of gonadotropin treatment in stimulating spermatogenesis in men with hypogonadotropic hypogonadism. When 21 men with hypogonadotropic hypogonadism were treated with human chorionic gonadotropin, the sperm count increased to within the normal range in the 6 in whom hypogonadism had begun after puberty, but in only 1 of the 15 in whom it had begun before puberty (P<0.002). When the remaining 14 men with prepubertal hypogonadism were treated with human menopausal gonadotropin in addition to human chorionic gonadotropin, the sperm count increased to normal in 5 of the 7 who had not had cryptorchidism, but in only 1 of the 7 who had (P<0.05). The need for human menopausal gonadotropin as a replacement for follicle-stimulating hormone could not be predicted by pretreatment serum and urinary levels of follicle-stimulating hormone.

    We conclude that gonadotropin treatment will usually increase the sperm count to normal in men with hypogonadotropic hypogonadism, unless cryptorchidism has occurred. The need for human menopausal gonadotropin treatment appears to depend on the time of onset of hypogonadism. (N Engl J Med 1985; 313:651–5.)
     
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    Last edited: Jan 30, 2011
  2. Ogre717

    Ogre717 TID Official Lab Rat

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    Interesting. My wife and i have been trying for a couple years now for kid #2 with no luck. My test resulte were in the high normal range but she is ovulating irregularly. I have been looking into ways to increase our odds some on my own and this looks like a valid option. How were these guys dosed?
     
    Last edited: Oct 30, 2011
  3. Cabo Jo

    Cabo Jo Thick n Wide VIP

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    I've got some HMG on the way.I hope I get huge balls and i'm spakeling the girls faces,lol.
     
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  4. rols

    rols VIP Member

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    it will increase the sperm count alot but it takes about 3-4months to really get the full effect going. I used it because me and my wife had fertility issues and I was on HRT (androgel).
     
  5. FlyingDragon

    FlyingDragon VIP Member

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    What protocol did your Fertility Specialist use for the HCG?


     
  6. Ogre717

    Ogre717 TID Official Lab Rat

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    Yea, id like to know too. My count isnt low but anything i can do to better our odds I am willing to try.
     
  7. Littleguy

    Littleguy Oldschool Veteran

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    Ogre, if you send me a pic of your wife, I may help you out with this issue:cool:
     
  8. dangerouscurves

    dangerouscurves TID Lady VIP

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    Has she been diagnosed with pcos??? I may have a couple safe things she can try that will increase your odds!
     
  9. Ogre717

    Ogre717 TID Official Lab Rat

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    the first couple of docs never tested her for it because she was thin, no facial hair, or other physical signs. the last doc has said she has some minor symptoms that may lead him to believe she has a mild case of pcos. Well i listen well and can google as good as the docs and she has more than a few symptoms that point to pcos. Please suggest away



    Shine: Would the dosing or HMG be the same protocol as on cycle HCG dosing?
     
  10. marx

    marx Oldschool Veteran

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    I got three balls and am actively not wanting to father anymore kids. I'll stear clear!
     
  11. rols

    rols VIP Member

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    let me dig up the old paperwork on it bro. I know i was dosing 3 times a week at first then dropped to two but have to look back for the iu of each dose. My wife self medicated with a trigger shot as well to make more eggs release, HCG does that for women too. I will get back tomorrow with some info for you guys.
     
  12. Ogre717

    Ogre717 TID Official Lab Rat

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    yea, we were doing the hcg trigger shots too with the docs. But im pretty sure they were timing the insemination wrong by about 12 hrs because i did a lot of researching on it and shit just wasnt adding up. Job security at its worst!
     

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