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Thymosin Beta 4(TB-500) Injury Healing

L

LILY

New Member
Jan 27, 2015
3
0
TB-500 helped my knees immensely. Just thought I would pass on what I learned. I dosed 2mg twice a week for one month. Prior to TB-500 I couldn't get off the toilet without using my hands to lift me off. This peptide does wonders for injury healing. Here is a recent study proving it speeds up healing of the MCL and other injuries. There are many studies regarding its healing properties.

Thymosin β4 enhances the healing of medial collateral ligament injury in rat.

AuthorsXu B, et al. Show all Journal
Regul Pept. 2013 Jun 10;184:1-5. doi: 10.1016/j.regpep.2013.03.026. Epub 2013 Mar 21.

ABSTRACT

The role pla by thymosin β4 (Tβ4) in the process of wound healing was reported in several organs. However, there have been no reports that investigated the role of Tβ4 in the repair process after ligament injury. The purpose of this study was to determine whether administration of Tβ4 would improve ligament repair following injury. The medial collateral ligament (MCL) was sharply transected on the day of surgery. Then, the treatment group received 100 μL of fibrin sealant containing 1 μg of Tβ4 placed in the ligament gap. Healing tissues were evaluated by hematoxylin and eosin stain, transmission electron microscopy, and biomechanical test at 4 weeks after surgery. Histologically, healing tissues in Tβ4-treated group exhibited uniform and evenly spaced fiber bundles. However, the collagen fibers were not evenly spaced in control rats. Moreover, diameters of collagen fibrils within granulation tissue from the Tβ4-treated rats were significantly increased. In Tβ4-treated MCLs, the mechanical properties of these healing tissues were significantly higher at 4 weeks after surgery. In terms of the mechanical properties of the healing femur-medial collateral ligament-tibia complexes, the Tβ4-treated group had significantly better biomechanical properties than the control group at 4 weeks after surgery. Local administration of Tβ4 promotes the healing process of MCL, both histologically and mechanically, in a rat model. These findings provide a basis for potential clinical use of Tβ4 in repairing ligaments.
 
Ironmike72

Ironmike72

Senior Member
Aug 13, 2012
217
10
Any studies on the ACL?? Had a replacement in '09. Still very problematic!!!! Also have issues with rght knee, mostly arthritis, recently had some cartilage removed. Any input on that either??? Thank in advance Bro.
 
georgia21

georgia21

Senior Member
Aug 30, 2010
124
8
I have heard TB-500 works well for speeding up the healing process but have not tried it yet. The keyword is "yet" I'm planning to order some today and see if it can help out my bum shoulder, I will keep you posted.
 
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